Due to the mobility of many pest species, effective integrated pest management (IPM) requires spatial coordination of management actions. This paper examines how the consideration of spatial dynamics, spatially coordinated collaboration, and supportive policy instruments improve pest management in agricultural landscapes. We consider empirical studies that explore the effects of spatial structure and processes on pest dynamics; conceptual frameworks that address larger spatial scales, such as Area-Wide Pest Management (AWPM); and policy instruments such as Payments for Ecosystem Services (PES) that have an impact on the land use in agricultural landscapes. The aim is to highlight how these three pillars of effective pest management are interrelated. Challenges and approaches for the establishment of spatial collaboration in agricultural pest management are identified and avenues for future research are presented.