Publication Details

Category Text Publication
Reference Category Journals
DOI 10.1016/j.copbio.2025.103321
Licence creative commons licence
Title (Primary) Carbon-efficient waste upcycling: combining syngas fermentation and chain elongation with synthetic consortia
Author Byung-Chul, R.K.; Kleinsteuber, S. ORCID logo ; Lawson, C.E.
Source Titel Current Opinion in Biotechnology
Year 2025
Department MIBITECH
Volume 94
Page From art. 103321
Language englisch
Topic T7 Bioeconomy
Abstract Syngas fermentation and chain elongation are key anaerobic biotechnologies for waste carbon upcycling. Their integration as a mixotrophic process enables simultaneous conversion of gaseous and wet waste substrates into medium-chain carboxylic acids and alcohols with high yields and no CO2 emissions. However, in practice, open culture-based processes suffer from low product yields, poor electron selectivity, and a narrow product range. Here, we explore synthetic consortia as a platform to advance one-pot mixotrophic waste conversion to medium-chain oleochemicals. We propose strategies for building synthetic consortia through a top-down, bottom-up approach, leveraging automation and high-throughput microbiology to accelerate bioprocess development. These advances could improve yields, expand waste feedstocks, and produce new chemicals, accelerating carbon-efficient waste upcycling toward industrial adoption while driving the circular economy.
Persistent UFZ Identifier https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=30935
Byung-Chul, R.K., Kleinsteuber, S., Lawson, C.E. (2025):
Carbon-efficient waste upcycling: combining syngas fermentation and chain elongation with synthetic consortia
Curr. Opin. Biotechnol. 94 , art. 103321 10.1016/j.copbio.2025.103321