Publication Details

Category Text Publication
Reference Category Journals
DOI 10.1002/hsr2.2201
Licence creative commons licence
Title (Primary) Tuberculosis and HIV/AIDS coinfection in patients attending Directly Observed Treatment Short-course (DOTS) centers in Anambra State, Nigeria: A retrospective study
Author Okeke, M.; Eze, P.M.; Chukwudebelu, A.E.; Nwankwo, C.J.; Eze, N.K.; Okafor, U.U.; Abonyi, I.C.; Okereke, E.E.; Obasi, K.O.; Ede, O.A.; Ejikeugwu, C.P.; Ilo, C.I.; Okafor, J.O.
Source Titel Health Science Reports
Year 2024
Department AME
Volume 7
Issue 6
Page From e2201
Language englisch
Topic T7 Bioeconomy
Keywords AIDS; Anambra; co-infection; HIV; Nigeria; prevalence; TB; tuberculosis
Abstract

Background and Aim(s)

This study retrospectively assessed the prevalence of TB and human immunodeficiency virus (HIV)/AIDS coinfection among patients that attended the Directly Observed Treatment Short-course (DOTS) centers in Anambra State, Southeast, Nigeria, between 2013 and 2017.

Methods

The study adopted a descriptive and retrospective epidemiological survey design. A total of 1443 case files of patients aged 15−60 who were treated in DOTS centers selected from Anambra State's 21 Local Government Areas between 2013 and 2017 were investigated. The uniform data form, a standardized instrument used in Anambra State's health facilities for data collection, was used to collect data from case files of all those identified as coinfected with TB and HIV/AIDS.

Results

The mean prevalence rate of TB and HIV/AIDS coinfection in the state during the 5-year period (2013–2017) was 20.00%. The highest annual prevalence of TB and HIV/AIDS coinfection was recorded in 2014 (23.84%). The state's prevalence of TB and HIV/AIDS coinfection increased dramatically from 13.17% in 2013 to 23.84% in 2014, followed by a slight downward trend to 22.80% in 2015, 20.17% in 2016, and 20.03% in 2017. In terms of gender, age, marital status, and occupation, females (59.5%), those aged 15 to 25 years (30.7%), married people (43.90%), and traders/business owners (50.7%), respectively, had the highest rates of tuberculosis and HIV/AIDS coinfection during the study period.

Conclusion

The findings of this study show that young people, females, married people, and traders/business owners appear to be the most vulnerable groups affected by TB and HIV/AIDS coinfection, accounting for the majority of the disease burden in the state. To address the high prevalence of TB and HIV/AIDS coinfection in the Anambra State, novel intervention and control programs should be developed and implemented, and existing intervention frameworks should be strengthened.

Persistent UFZ Identifier https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=29345
Okeke, M., Eze, P.M., Chukwudebelu, A.E., Nwankwo, C.J., Eze, N.K., Okafor, U.U., Abonyi, I.C., Okereke, E.E., Obasi, K.O., Ede, O.A., Ejikeugwu, C.P., Ilo, C.I., Okafor, J.O. (2024):
Tuberculosis and HIV/AIDS coinfection in patients attending Directly Observed Treatment Short-course (DOTS) centers in Anambra State, Nigeria: A retrospective study
Health Sci Rep. 7 (6), e2201 10.1002/hsr2.2201