Publication Details

Category Text Publication
Reference Category Journals
DOI 10.1016/j.envint.2024.108585
Licence creative commons licence
Title (Primary) Innovative analytical methodologies for characterizing chemical exposure with a view to next-generation risk assessment
Author Tkalec, Ž.; Antignac, J.-P.; Bandow, N.; Béen, F.M.; Belova, L.; Bessems, J.; Le Bizec, B.; Brack, W.; Cano-Sancho, G.; Chaker, J.; Covaci, A.; Creusot, N.; David, A.; Debrauwer, L.; Dervilly, G.; Duca, R.C.; Fessard, V.; Grimalt, J.O.; Guerin, T.; Habchi, B.; Hecht, H.; Hollender, J.; Jamin, E.L.; Klánová, J.; Kosjek, T.; Krauss, M. ORCID logo ; Lamoree, M.; Lavison-Bompard, G.; Meijer, J.; Moeller, R.; Mol, H.; Mompelat, S.; Van Nieuwenhuyse, A.; Oberacher, H.; Parinet, J.; Van Poucke, C.; Roškar, R.; Togola, A.; Trontelj, J.; Price, E.J.
Source Titel Environment International
Year 2024
Department EXPO
Volume 186
Page From art. 108585
Language englisch
Topic T9 Healthy Planet
Keywords High-resolution mass spectrometry; Effect-based methods; Sampling strategies; Chemical exposure; Chemical risk assessment; Effect-directed analysis
Abstract The chemical burden on the environment and human population is increasing. Consequently, regulatory risk assessment must keep pace to manage, reduce, and prevent adverse impacts on human and environmental health associated with hazardous chemicals. Surveillance of chemicals of known, emerging, or potential future concern, entering the environment-food-human continuum is needed to document the reality of risks posed by chemicals on ecosystem and human health from a one health perspective, feed into early warning systems and support public policies for exposure mitigation provisions and safe and sustainable by design strategies. The use of less-conventional sampling strategies and integration of full-scan, high-resolution mass spectrometry and effect-directed analysis in environmental and human monitoring programmes have the potential to enhance the screening and identification of a wider range of chemicals of known, emerging or potential future concern. Here, we outline the key needs and recommendations identified within the European Partnership for Assessment of Risks from Chemicals (PARC) project for leveraging these innovative methodologies to support the development of next-generation chemical risk assessment.
Persistent UFZ Identifier
Tkalec, Ž., Antignac, J.-P., Bandow, N., Béen, F.M., Belova, L., Bessems, J., Le Bizec, B., Brack, W., Cano-Sancho, G., Chaker, J., Covaci, A., Creusot, N., David, A., Debrauwer, L., Dervilly, G., Duca, R.C., Fessard, V., Grimalt, J.O., Guerin, T., Habchi, B., Hecht, H., Hollender, J., Jamin, E.L., Klánová, J., Kosjek, T., Krauss, M., Lamoree, M., Lavison-Bompard, G., Meijer, J., Moeller, R., Mol, H., Mompelat, S., Van Nieuwenhuyse, A., Oberacher, H., Parinet, J., Van Poucke, C., Roškar, R., Togola, A., Trontelj, J., Price, E.J. (2024):
Innovative analytical methodologies for characterizing chemical exposure with a view to next-generation risk assessment
Environ. Int. 186 , art. 108585 10.1016/j.envint.2024.108585