Publication Details |
| Category | Text Publication |
| Reference Category | Journals |
| DOI | 10.1016/0168-1656(93)90074-W |
| Title (Primary) | Development of a process-FIA system using mediator-modified enzyme electrodes |
| Author | Gründig, B.; Strehlitz, B.; Kotte, H.; Ethner, K. |
| Source Titel | Journal of Biotechnology |
| Year | 1993 |
| Department | UBT; UBZ; SAN |
| Volume | 31 |
| Issue | 3 |
| Page From | 277 |
| Page To | 287 |
| Language | englisch |
| Keywords | Flow injection analysis; FIA; Biosensor; Process control; Glucose |
| Abstract | A computer-controlled process-FIA system for monitoring industrial bioprocesses was developed using mediator-modified enzyme electrodes. The single-line FIA system was modified by replacing the mixing coil with a flexible operating sample dilution unit. By this way, the analyzer offers automatic procedures for self-calibration ‘real-time’ dilution and recalibration based on the current analyte concentration. In regard to the dynamic range of the sensors, the FIA system is able to self-adapting to any analyte concentration of the bioprocess. The technique was tested for control of glucose during microbial fed-batch processes of gluconic acid production. |
| Persistent UFZ Identifier | https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=27826 |
| Gründig, B., Strehlitz, B., Kotte, H., Ethner, K. (1993): Development of a process-FIA system using mediator-modified enzyme electrodes J. Biotechnol. 31 (3), 277 - 287 10.1016/0168-1656(93)90074-W |
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