Publication Details |
| Category | Text Publication |
| Reference Category | Journals |
| DOI | 10.1080/00211919208050831 |
| Title (Primary) | 15N NMR of glycine metabolism in liver, muscle and kidney of rats using a new pulsed overhauser technique (POE) |
| Author | Gründer, W.; Krumbiegel, P.; Gersonde, K. |
| Source Titel | Isotopenpraxis |
| Year | 1992 |
| Department | ISOBIO; EXPOEPID |
| Volume | 28 |
| Issue | 1 |
| Page From | 81 |
| Page To | 84 |
| Language | englisch |
| Keywords | Diagnostic techniques, glycine, metabolism, nitrogen 15, nuclear magnetic resonance spectroscopy, Overhauser techniques, rats |
| Abstract | Following intravenous injections of ["N]glycine (97 at.% "N, 4Wmg in 1.5 ml isotonic saline) to Lewis rzts several organs were excised. The time courses of the "N NMR spectral (40.55 MHz) were measured at 37°C after cold (4°C) or warm (37°C) storage. The application of the Ovcrhauser POE technique yielded signal enhancement by a factor of -2.7 and -1.3 in sceletal and heart muscle, respectively, at 37"C, but no enhancement in liver and kidney. In the time course of liver measurements at 37°C. intermediate metabolic products of glycinc were observed, such as serine, glutamine, alanine, and tryptophane |
| Persistent UFZ Identifier | https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=27741 |
| Gründer, W., Krumbiegel, P., Gersonde, K. (1992): 15N NMR of glycine metabolism in liver, muscle and kidney of rats using a new pulsed overhauser technique (POE) Isotopenpraxis 28 (1), 81 - 84 10.1080/00211919208050831 |
|