Publication Details

Category Text Publication
Reference Category Journals
DOI 10.2166/wh.2022.165
Licence creative commons licence
Title (Primary) Effect-based monitoring to integrate the mixture hazards of chemicals into water safety plans
Author Neale, P.A.; Escher, B.I.; de Baat, M.L.; Dechesne, M.; Deere, D.A.; Enault, J.; Kools, S.A.E.; Loret, J.-F.; Smeets, P.W.M.H.; Leusch, F.D.L.
Source Titel Journal of Water and Health
Year 2022
Department ZELLTOX
Volume 20
Issue 12
Page From 1721
Page To 1732
Language englisch
Topic T9 Healthy Planet
Keywords drinking water; in vitro bioassays; micropollutants; water quality monitoring; water safety plan; well plate-based in vivo assays
Abstract Water safety plans (WSPs) are intended to assure safe drinking water (DW). WSPs involve assessing and managing risks associated with microbial, chemical, physical and radiological hazards from the catchment to the consumer. Currently, chemical hazards in WSPs are assessed by targeted chemical analysis, but this approach fails to account for the mixture effects of the many chemicals potentially present in water supplies and omits the possible effects of non-targeted chemicals. Consequently, effect-based monitoring (EBM) using in vitro bioassays and well plate-based in vivo assays are proposed as a complementary tool to targeted chemical analysis to support risk analysis, risk management and water quality verification within the WSP framework. EBM is frequently applied to DW and surface water and can be utilised in all defined monitoring categories within the WSP framework (including ‘system assessment’, ‘validation’, ‘operational’ and ‘verification’). Examples of how EBM can be applied within the different WSP modules are provided, along with guidance on where to apply EBM and how frequently. Since this is a new area, guidance documents, standard operating procedures (SOPs) and decision-making frameworks are required for both bioassay operators and WSP teams to facilitate the integration of EBM into WSPs, with these resources being developed currently.
Persistent UFZ Identifier https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=26864
Neale, P.A., Escher, B.I., de Baat, M.L., Dechesne, M., Deere, D.A., Enault, J., Kools, S.A.E., Loret, J.-F., Smeets, P.W.M.H., Leusch, F.D.L. (2022):
Effect-based monitoring to integrate the mixture hazards of chemicals into water safety plans
J. Water Health 20 (12), 1721 - 1732 10.2166/wh.2022.165