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Title (Primary) Cyanobacteria as whole-cell factories: current status and future prospectives
Author Toepel, J.; Karande, R.; Klähn, S.; Bühler, B.
Journal Current Opinion in Biotechnology
Year 2023
Department UMB; SOMA
Volume 80
Page From art. 102892
Language englisch
Topic T7 Bioeconomy
Abstract Cyanobacteria as phototrophic microorganisms bear great potential to produce chemicals from sustainable resources such as light and CO2. Most studies focus on either strain engineering or tackling metabolic constraints. Recently gained knowledge on internal electron and carbon fluxes and their regulation provides new opportunities to efficiently channel cellular resources toward product formation. Concomitantly, novel photobioreactor concepts are developed to ensure sufficient light supply. This review summarizes the newest developments in the field of cyanobacterial engineering to finally establish photosynthesis-based production processes. A holistic approach tackling genetic, metabolic, and biochemical engineering in parallel is considered essential to turn their application into an ecoefficient and economically feasible option for a future green bioeconomy.
Persistent UFZ Identifier https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=25473
Toepel, J., Karande, R., Klähn, S., Bühler, B. (2023):
Cyanobacteria as whole-cell factories: current status and future prospectives
Curr. Opin. Biotechnol. 80 , art. 102892