Publication Details

Category Text Publication
Reference Category Journals
DOI 10.1016/j.jhazmat.2023.131009
Document author version
Title (Primary) Wastewater-based epidemiology for the assessment of population exposure to chemicals: The need for integration with human biomonitoring for global One Health actions
Author Kasprzyk-Hordern, B.; Béen, F.; Bijlsma, L.; Brack, W.; Castiglioni, S.; Covaci, A.; Martincigh, B.S.; Mueller, J.F.; van Nuijs, A.L.N.; Oluseyi, T.; Thomas, K.V.
Source Titel Journal of Hazardous Materials
Year 2023
Department WANA
Volume 450
Page From art. 131009
Language englisch
Topic T9 Healthy Planet
Keywords Wastewater-Based Epidemiology (WBE); human chemical exposure; One Health; Mass spectrometry; Human Biomonitoring (HBM)
Abstract WBE has now become a complimentary tool in SARS-CoV-2 surveillance. This was preceded by the established application of WBE to assess the consumption of illicit drugs in communities. It is now timely to build on this and take the opportunity to expand WBE to enable comprehensive assessment of community exposure to chemical stressors and their mixtures. The goal of WBE is to quantify community exposure, discover exposure-outcome associations, and trigger policy, technological or societal intervention strategies with the overarching aim of exposure prevention and public health promotion. To achieve WBE’s full potential, the following key aspects require further action: (1) Integration of WBE-HBM (human biomonitoring) initiatives that provide comprehensive community-individual multichemical exposure assessment. (2) Global WBE monitoring campaigns to provide much needed data on exposure in low- and middle-income countries (LMICs) and fill in the gaps in knowledge especially in the underrepresented highly urbanised as well as rural settings in LMICs. (3) Combining WBE with One Health actions to enable effective interventions. (4) Advancements in new analytical tools and methodologies for WBE progression to enable biomarker selection for exposure studies, and to provide sensitive and selective multiresidue analysis for trace multi-biomarker quantification in a complex wastewater matrix. Most of all, further developments of WBE needs to be undertaken by co-design with key stakeholder groups: government organisations, health authorities and private sector.
Persistent UFZ Identifier https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=24742
Kasprzyk-Hordern, B., Béen, F., Bijlsma, L., Brack, W., Castiglioni, S., Covaci, A., Martincigh, B.S., Mueller, J.F., van Nuijs, A.L.N., Oluseyi, T., Thomas, K.V. (2023):
Wastewater-based epidemiology for the assessment of population exposure to chemicals: The need for integration with human biomonitoring for global One Health actions
J. Hazard. Mater. 450 , art. 131009 10.1016/j.jhazmat.2023.131009