Publication Details |
| Category | Text Publication |
| Reference Category | Journals |
| DOI | 10.1007/s00284-005-0239-z |
| Document | Shareable Link |
| Title (Primary) | Biotransformation of 1-naphthol by a strictly aquatic fungus |
| Author | Augustin, T.; Schlosser, D.
; Baumbach, R.; Schmidt, J.; Grancharov, K.; Krauss, G.; Krauss, G.-J. |
| Source Titel | Current Microbiology |
| Year | 2006 |
| Department | UMB |
| Volume | 52 |
| Issue | 3 |
| Page From | 216 |
| Page To | 220 |
| Language | englisch |
| Abstract | The aquatic hyphomycete Heliscus lugdunensis belongs to a group of exclusively aquatic mitosporic fungi with an only scarcely explored potential to oxidatively attack xenobiotic compounds, and was used to study the biotransformation of the environmental pollutant metabolite 1-naphthol. H. lugdunensis metabolized approximately 74% of 1-naphthol within 5 days. The identification and quantification of degradation products using gas chromatography-mass spectrometry, liquid chromatography-mass spectrometry, and high performance liquid chromatography revealed that approximately 12% of the parent compound was converted into 1-naphthylsulfate, 3% was transformed into 1-methoxy-naphthalene, and less than 1% was converted into 1,4-naphthoquinone. A further metabolite, most likely 4-hydroxy-1-naphthylsulfate, was also detected. In contrast to sulfate conjugate metabolites, no glucuronide and glucoside conjugates of 1-naphthol were found, and neither UDP-glucuronyltransferase nor UDP-glucosyltransferase present in H. lugdunensis showed activity towards 1-naphthol. These results support a role of fungi adapted to aquatic environments in affecting the environmental fate of pollutants in aquatic ecosystems. |
| Augustin, T., Schlosser, D., Baumbach, R., Schmidt, J., Grancharov, K., Krauss, G., Krauss, G.-J. (2006): Biotransformation of 1-naphthol by a strictly aquatic fungus Curr. Microbiol. 52 (3), 216 - 220 10.1007/s00284-005-0239-z |
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