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Title (Primary) Environmental factors and host microbiomes shape host–pathogen dynamics
Author Bernardo-Cravo, A.P.; Schmeller, D.S.; Chatzinotas, A.; Vredenburg, V.T.; Loyau, A.;
Journal Trends in Parasitology
Year 2020
Department UMB; iDiv;
Volume 36
Issue 7
Language englisch;
POF III (all) T32;
Keywords parasite; fungi; Anthropocene; disease triangle; habitat degradation; disease pyramid
Abstract Microorganisms are increasingly recognized as ecosystem-relevant components because they affect the population dynamics of hosts. Functioning at the interface of the host and pathogen, skin and gut microbiomes are vital components of immunity. Recent work reveals a strong influence of biotic and abiotic environmental factors (including the environmental microbiome) on disease dynamics, yet the importance of the host–host microbiome–pathogen–environment interaction has been poorly reflected in theory. We use amphibians and the disease chytridiomycosis caused by the fungal pathogen Batrachochytrium dendrobatidis to show how interactions between host, host microbiome, pathogen, and the environment all affect disease outcome. Our review provides new perspectives that improve our understanding of disease dynamics and ecology by incorporating environmental factors and microbiomes into disease theory.
ID 23157
Persistent UFZ Identifier
Bernardo-Cravo, A.P., Schmeller, D.S., Chatzinotas, A., Vredenburg, V.T., Loyau, A. (2020):
Environmental factors and host microbiomes shape host–pathogen dynamics
Trends Parasitol. 36 (7), 616 - 633