Publication Details

Category Text Publication
Reference Category Journals
DOI 10.1007/s00216-020-02722-5
Licence creative commons licence
Title (Primary) A rapid method for quantification of persistent and mobile organic substances in water using supercritical fluid chromatography coupled to high-resolution mass spectrometry
Author Schulze, S.; Paschke, H.; Meier, T.; Muschket, M.; Reemtsma, T.; Berger, U.
Source Titel Analytical and Bioanalytical Chemistry
Year 2020
Department ANA
Volume 412
Issue 20
Page From 4941
Page To 4952
Language englisch
Supplements https://static-content.springer.com/esm/art%3A10.1007%2Fs00216-020-02722-5/MediaObjects/216_2020_2722_MOESM1_ESM.docx
Keywords Persistent and mobile organic substances; PM substances; PMOCs; Supercritical fluid chromatography; Evaporation; Water samples
Abstract Persistent and mobile organic substances (PM substances) are a threat to the quality of our water resources. While screening studies revealed widespread occurrence of many PM substances, rapid trace analytical methods for their quantification in large sample sets are missing. We developed a quick and generic analytical method for highly mobile analytes in surface water, groundwater, and drinking water samples based on enrichment through azeotrope evaporation (4 mL water and 21 mL acetonitrile), supercritical fluid chromatography (SFC) coupled to high-resolution mass spectrometry (HRMS), and quantification using a compound-specific correction factor for apparent recovery. The method was validated using 17 PM substances. Sample preparation recoveries were between 60 and 110% for the vast majority of PM substances. Strong matrix effects (most commonly suppressive) were observed, necessitating a correction for apparent recoveries in quantification. Apparent recoveries were neither concentration dependent nor dependent on the water matrix (surface or drinking water). Method detection and quantification limits were in the single- to double-digit ng L−1 ranges, precision expressed as relative standard deviation of quadruplicate quantifications was on average < 10%, and trueness experiments showed quantitative results within ± 30% of the theoretical value in 77% of quantifications. Application of the method to surface water, groundwater, raw water, and finished drinking water revealed the presence of acesulfame and trifluoromethanesulfonic acid up to 70 and 19 μg L−1, respectively. Melamine, diphenylguanidine, p-dimethylbenzenesulfonic acid, and 4-hydroxy-1-(2-hydroxyethyl)-2,2,6,6-tetramethylpiperidine were found in high ng L−1 concentrations.
Persistent UFZ Identifier https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=23130
Schulze, S., Paschke, H., Meier, T., Muschket, M., Reemtsma, T., Berger, U. (2020):
A rapid method for quantification of persistent and mobile organic substances in water using supercritical fluid chromatography coupled to high-resolution mass spectrometry
Anal. Bioanal. Chem. 412 (20), 4941 - 4952 10.1007/s00216-020-02722-5