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Title (Primary) Process design for the microbial synthesis of poly-β-hydroxybutyrate (PHB) from natural gas
Author Listewnik, H.-F.; Wendlandt, K.-D.; Jechorek, M.; Mirschel, G.;
Journal Engineering in Life Sciences
Year 2007
Department UBT;
Volume 7
Issue 3
Language englisch;
Keywords biosynthesis; costs; PHB; process design
Abstract A process design for a two-stage procedure for the production of PHB from natural gas based on the results, obtained on a laboratory and small technical scale, was developed. For this purpose, four bioreactors were dimensioned and interconnected so as to achieve a quasi-continuous PHB production. A price of 6.35 /kg PHB was pre-calculated for the biosynthesis in a plant producing 500 t PHB/year. An extrapolation, which included the incorporation of various downstream procedures to achieve purities dependent on applications, resulted in prices between 11.50 and 14.00 /kg for the purified final product. Estimations indicate that an expansion of the plant capacity to 5,000 t/year could enable a price reduction of approx. 30-35 %.
ID 2018
Persistent UFZ Identifier https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=2018
Listewnik, H.-F., Wendlandt, K.-D., Jechorek, M., Mirschel, G. (2007):
Process design for the microbial synthesis of poly-β-hydroxybutyrate (PHB) from natural gas
Eng. Life Sci. 7 (3), 278 - 282