Publication Details

Category Text Publication
Reference Category Journals
DOI 10.1016/j.cej.2015.11.047
Title (Primary) Degradation of the antiviral drug zanamivir in wastewater – The potential of a photocatalytic treatment process
Author Woche, M.; Scheibe, N.; von Tümpling, W. ORCID logo ; Schwidder, M.
Source Titel Chemical Engineering Journal
Year 2016
Department FLOEK
Volume 287
Page From 674
Page To 679
Language englisch
Keywords Wastewater treatment; Photocatalysis; UV radiation; Titanium dioxide; Zanamivir; Raw cost estimation
UFZ wide themes RU2;
Abstract The antiviral drug zanamivir counteracts the influenza A and B viruses by preventing the infection of further healthy cells. In pandemic cases, large amounts will be administered and will therefore enter the wastewater. For this reason the potential of a photocatalytic wastewater treatment process aiming at the degradation of zanamivir was explored using aqueous solutions of zanamivir and the primary transformation product guanidine, which were irradiated with UV light under various conditions in the presence of TiO2 as a photocatalyst. By studying the transformation behavior of these substances it can be demonstrated that using TiO2 as a photocatalyst can accelerate the transformation of zanamivir. Simultaneously, however, this leads to a decrease of photon efficiency due to turbidity. Based on these findings, an optimization of the amount of TiO2 suspended in aqueous zanamivir solutions during irradiation and a first rough cost estimate were carried out. Further results show that guanidine cannot be transformed using UV radiation and TiO2 as a photocatalyst.
Persistent UFZ Identifier https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=16890
Woche, M., Scheibe, N., von Tümpling, W., Schwidder, M. (2016):
Degradation of the antiviral drug zanamivir in wastewater – The potential of a photocatalytic treatment process
Chem. Eng. J. 287 , 674 - 679 10.1016/j.cej.2015.11.047