Publication Details

Category Text Publication
Reference Category Journals
DOI 10.1021/es505837v
Title (Primary) Kinetics of substrate biodegradation under the cumulative effects of bioavailability and self-inhibition
Author Gharasoo, M.; Centler, F.; van Cappellen, P.; Wick, L.Y.; Thullner, M.
Source Titel Environmental Science & Technology
Year 2015
Department UMB
Volume 49
Issue 9
Page From 5529
Page To 5537
Language englisch
Keywords Substrate Inhibition; Bioavailability; Bioremediation; Contaminant Biodegradation; Biogeosciences
UFZ wide themes RU3;
Abstract Microbial degradation is an important process in many environments controlling for instance the cycling of nutrients or the biodegradation of contaminants. At high substrate concentrations toxic effects may inhibit the degradation process. Bioavailability limitations of a degradable substrate can therefore either improve the overall dynamics of degradation by softening the contaminant toxicity effects to microorganisms, or slow down the biodegradation by reducing the microbial access to the substrate. Many studies on biodegradation kinetics of a self-inhibitive substrate have mainly focused on physiological responses of the bacteria to substrate concentration levels without considering the substrate bioavailability limitations rising from different geophysical and geochemical dynamics at pore-scale. In this regard, the role of bioavailability effects on the kinetics of self-inhibiting substrates is poorly understood. In this study, we theoretically analyze this role and assess the interactions between self-inhibition and mass transfer-limitations using analytical/numerical solutions, and show the findings practical relevance for a simple model scenario. Although individually self-inhibition and mass-transfer limitations negatively impact biodegradation, their combined effect may enhance biodegradation rates above a concentration threshold. To our knowledge, this is the first theoretical study describing the cumulative effects of the two mechanisms together.
Persistent UFZ Identifier
Gharasoo, M., Centler, F., van Cappellen, P., Wick, L.Y., Thullner, M. (2015):
Kinetics of substrate biodegradation under the cumulative effects of bioavailability and self-inhibition
Environ. Sci. Technol. 49 (9), 5529 - 5537 10.1021/es505837v