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Title (Primary) Determination and identification of hydrophilic and hydrophobic arsenic species in methanol extract of fresh cod liver by RP-HPLC with simultaneous ICP-MS and ESI-Q-TOF-MS detection
Author Arroyo-Abad, U.; Lischka, S.; Piechotta, C.; Mattusch, J.; Reemtsma, T.
Journal Food Chemistry
Year 2013
Department ANA
Volume 141
Issue 3
Page From 3093
Page To 3102
Language englisch
Keywords Arsenic species; Arsenolipids; Marine fish; Cod liver; HPLC-ICP-MS/ESI-Q-TOF-MS
UFZ wide themes RU4;
Abstract

The present study was focused on the determination and identification of arsenic species in methanolic extracts of cod liver. Arsenic species were fractionated and the fractions analysed by RP-HPLC-ICP-MS coupled with ESI-Q-TOF-MS. The total concentration of arsenic in the fresh cod liver was analysed by ICP-MS to be 1.53 ± 0.02 mg As kg−1 w.w. and the extraction recovery was ca. 100% and the column recovery >93%. Besides polar inorganic and methylated arsenic species (>70%) more hydrophobic arsenic-containing fatty acids and hydrocarbons occurred. Based on the mass spectrometric data proposals for molecular structures were elaborated for 20 of the organic As species included 10 arsenic-containing fatty acids (AsFA) and an arsenic-containing hydrocarbon (AsHC) mentioned for the first time in fresh cod liver. Arsenobetaine was found as main water-soluble arsenic compound in cod liver followed by higher molecular mass arsenic-containing fatty acids and hydrocarbons.

Persistent UFZ Identifier https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=13994
Arroyo-Abad, U., Lischka, S., Piechotta, C., Mattusch, J., Reemtsma, T. (2013):
Determination and identification of hydrophilic and hydrophobic arsenic species in methanol extract of fresh cod liver by RP-HPLC with simultaneous ICP-MS and ESI-Q-TOF-MS detection
Food Chem. 141 (3), 3093 - 3102