Publication Details

Category Text Publication
Reference Category Journals
DOI 10.1016/j.cep.2007.02.014
Title (Primary) Chip calorimetry and its use for biochemical and cell biological investigations
Author Lerchner, J.; Maskow, T. ORCID logo ; Wolf, G.
Source Titel Chemical Engineering and Processing
Year 2008
Department UMB
Volume 47
Issue 6
Page From 991
Page To 999
Language englisch
Keywords Chip calorimeter; Biothermodynamics; Metabolic heat; Enzyme activity; Bioreactor; chip calorimeter; biothermodynamics; metabolic heat; enzyme activity; bioreactor
Abstract The presented paper analyzes the potential of chip calorimetry for biochemical and cell biological investigations. From the thermo-physical properties of the heat power detectors of a chip calorimeter can be deduced that relevant applications mainly refer to fast reactions in extremely small samples. In contrast, the use of chip calorimeters for studying slow processes such as biochemical or microbial reactions is restricted. However, careful optimization of chip calorimeters concerning signal resolution and sample volume enables the investigation of enzymatically catalyzed reactions and the measurement of microbial growth heat as subsequently demonstrated with some typical examples from the literature.
Persistent UFZ Identifier https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=1184
Lerchner, J., Maskow, T., Wolf, G. (2008):
Chip calorimetry and its use for biochemical and cell biological investigations
Chem. Eng. Process. 47 (6), 991 - 999 10.1016/j.cep.2007.02.014