Publication Details

Category Text Publication
Reference Category Journals
DOI 10.1016/j.jhazmat.2011.10.004
Title (Primary) Biodegradation of ciprofloxacin in water and soil and its effects on the microbial communities
Author Girardi, C.; Greve, J.; Lamshöft, M.; Fetzer, I.; Miltner, A. ORCID logo ; Schäffer, A.; Kästner, M.
Source Titel Journal of Hazardous Materials
Year 2011
Department UMB; UBT; GWS
Volume 198
Page From 22
Page To 30
Language englisch
Keywords Ciprofloxacin; Radiotracer; Biodegradation; Bioavailability; Toxicity
Abstract

While antibiotics are frequently found in the environment, their biodegradability and ecotoxicological effects are not well understood. Ciprofloxacin inhibits active and growing microorganisms and therefore can represent an important risk for the environment, especially for soil microbial ecology and microbial ecosystem services. We investigated the biodegradation of 14C-ciprofloxacin in water and soil following OECD tests (301B, 307) to compare its fate in both systems. Ciprofloxacin is recalcitrant to biodegradation and transformation in the aqueous system. However, some mineralisation was observed in soil. The lower bioavailability of ciprofloxacin seems to reduce the compound's toxicity against microorganisms and allows its biodegradation. Moreover, ciprofloxacin strongly inhibits the microbial activities in both systems. Higher inhibition was observed in water than in soil and although its antimicrobial potency is reduced by sorption and aging in soil, ciprofloxacin remains biologically active over time. Therefore sorption does not completely eliminate the effects of this compound.
Persistent UFZ Identifier https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=11801
Girardi, C., Greve, J., Lamshöft, M., Fetzer, I., Miltner, A., Schäffer, A., Kästner, M. (2011):
Biodegradation of ciprofloxacin in water and soil and its effects on the microbial communities
J. Hazard. Mater. 198 , 22 - 30