Publication Details

Reference Category Book chapters
DOI / URL
Title (Primary) Does virulence decline by time in wild boar populations infected by Classical Swine Fever virus (CSFV)?
Title (Secondary) Society for Veterinary Epidemiology and Preventive Medicine: Proceedings of a meeting held in Leipzig, Germany, 23rd-25th March 2011
Author Lange, M.; Kramer-Schadt, S.; Thulke, H.-H.;
Publisher Fourichon, C.; Pfeiffer, D.U.;
Year 2011
Department OESA;
Language englisch;
Abstract Classical Swine Fever (CSF) is an endemic viral disease in European wild boar populations causing high economic impact to the pig farming industry. Virulence is a crucial factor determining persistence in local wild boar populations. We considered shift in virulence on the time scale of recent outbreaks using an individual-based spatially-explicit model which represents knowledge on wild boar ecology and CSF virus epidemiology. Two alternative scenarios were supposed as reasonable mechanisms that shift virulence pattern: 1) evolution of pathogen's virulence and 2) selection for host resistance. With both processes we found a possible short term shift to lower virulence. Pathogen evolution, however, resulted in faster decline down to a threshold level, while host selection resulted in slower but continuous decline of virulence. Both mechanisms promoted disease persistence.
ID 11017
Persistent UFZ Identifier https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=11017
Lange, M., Kramer-Schadt, S., Thulke, H.-H. (2011):
Does virulence decline by time in wild boar populations infected by Classical Swine Fever virus (CSFV)?
In: Fourichon, C., Pfeiffer, D.U. (eds.)
Society for Veterinary Epidemiology and Preventive Medicine: Proceedings of a meeting held in Leipzig, Germany, 23rd-25th March 2011
Society for Veterinary Epidemiology and Preventive Medicine, p. 154 - 167