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DOI 10.1007/s00216-010-4339-7
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Title (Primary) GC-MS determination of parabens, triclosan and methyl triclosan in water by in situ derivatisation and stir-bar sorptive extraction
Author Casas Ferreira, A.M.; Möder, M.; Fernández Laespada, M.E.
Source Titel Analytical and Bioanalytical Chemistry
Year 2011
Department ANA
Volume 399
Issue 2
Page From 945
Page To 953
Language englisch
Keywords Stir-bar sorptive extraction; In situ derivatisation; Parabens; Water; Wastewater
Abstract Stir-bar sorptive extraction in combination with an in situ derivatisation reaction and thermal desorption-gas chromatography-mass spectrometry was successfully applied to determine parabens (methylparaben, isopropylparaben, n-propylparaben, butylparaben and benzylparaben), triclosan and methyltriclosan in water samples. This approach improves both the extraction efficiency and the sensitivity in the GC in a simple way since the derivatisation reaction occurs at the same time as the extraction procedure. The in situ derivatisation reaction was carried out with acetic anhydride under alkaline conditions. Thermal desorption parameters (cryofocusing temperature, desorption flow, desorption time, desorption temperature) were optimised using a Box-Behnken experimental design. All the analytes gave recoveries higher than 79%, except methylparaben (22%). The method afforded detection limits between 0.64 and 4.12 ng/L, with good reproducibility and accuracy values. The feasibility of the method for the determination of analytes in water samples was checked in tap water and untreated and treated wastewater.
Persistent UFZ Identifier https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=10729
Casas Ferreira, A.M., Möder, M., Fernández Laespada, M.E. (2011):
GC-MS determination of parabens, triclosan and methyl triclosan in water by in situ derivatisation and stir-bar sorptive extraction
Anal. Bioanal. Chem. 399 (2), 945 - 953 10.1007/s00216-010-4339-7