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15722 Altenburger, R., Ait-Aissa, S., Antczak, P., Backhaus, T., Barceló, D., Seiler, T.-B., Brion, F., Busch, W., Chipman, K., López de Alda, M., De Aragão Umbuzeiro, G., Escher, B.I., Falciani, F., Faust, M., Focks, A., Hilscherova, K., Hollender, J., Hollert, H., Jäger, F., Jahnke, A., Kortenkamp, A., Krauss, M., Lemkine, G.F., Munthe, J., Neumann, S., Schymanski, E.L., Scrimshaw, M., Segner, H., Slobodnik, J., Smedes, F., Kughathas, S., Teodorovic, I., Tindall, A.J., Tollefsen, K.E., Walz, K.-H., Williams, T.D., van den Brink, P.J., van Gils, J., Vrana, B., Zhang, X., Brack, W. (2015):
Future water quality monitoring — Adapting tools to deal with mixtures of pollutants in water resource management
Sci. Total Environ. 512-513 , 540 - 551
full text (doi)
21602 Altenburger, R., Brack, W., Burgess, R.M., Busch, W., Escher, B.I., Focks, A., Hewitt, L.M., Jacobsen, B.N., López de Alda, M., Ait-Aissa, S., Backhaus, T., Ginebreda, A., Hilscherová, K., Hollender, J., Hollert, H., Neale, P.A., Schulze, T., Schymanski, E.L., Teodorovic, I., Tindall, A.J., De Aragão Umbuzeiro, G., Vrana, B., Zonja, B., Krauss, M. (2019):
Future water quality monitoring: improving the balance between exposure and toxicity assessments of real-world pollutant mixtures
Environ. Sci. Eur. 31 , art. 12
full text (doi)
12166 Altenburger, R., Scholz, S., Schmitt-Jansen, M., Busch, W., Escher, B.I. (2012):
Mixture toxicity revisited from a toxicogenomic perspective
Environ. Sci. Technol. 46 (5), 2508 - 2522
full text (doi)
19970 Altenburger, R., Scholze, M., Busch, W., Escher, B.I., Jakobs, G., Krauss, M., Krüger, J., Neale, P.A., Ait-Aissa, S., Almeida, A.C., Seiler, T.-B., Brion, F., Hilscherová, K., Hollert, H., Novák, J., Schlichting, R., Serra, H., Shao, Y., Tindall, A., Tolefsen, K.-E., Umbuzeiro, G., Williams, T.D., Kortenkamp, A. (2018):
Mixture effects in samples of multiple contaminants – An inter-laboratory study with manifold bioassays
Environ. Int. 114 , 95 - 106
full text (doi)
41 Bastian, S., Busch, W., Kühnel, D., Springer, A., Meißner, T., Holke, R., Scholz, S., Iwe, M., Pompe, W., Gelinsky, M., Potthoff, A., Richter, V., Ikonomidou, H., Schirmer, K. (2009):
Toxicity of tungsten carbide and cobalt-doped tungsten carbide nanoparticles in mammalian cells in vitro
Environ. Health Perspect. 117 (4), 530 - 536
full text (doi)
19926 Beckers, L.-M., Busch, W., Krauss, M., Schulze, T., Brack, W. (2018):
Characterization and risk assessment of seasonal and weather dynamics in organic pollutant mixtures from discharge of a separate sewer system
Water Res. 135 , 122 - 133
full text (doi)
15153 Böhme, S., Stärk, H.-J., Meißner, T., Springer, A., Reemtsma, T., Kühnel, D., Busch, W. (2014):
Quantification of Al2O3 nanoparticles in human cell lines applying inductively coupled plasma mass spectrometry (neb-ICP-MS, LA-ICP-MS) and flow cytometry-based methods
J. Nanopart. Res. 16 , 2592
full text (doi)
93 Böselt, I., Römpler, H., Hermsdorf, T., Thor, D., Busch, W., Schulz, A., Schöneberg, T. (2009):
Involvement of the V2 vasopressin receptor in adaptation to limited water supply
PLoS One 4 (5), e5573
full text (doi)
16992 Brack, W., Ait-Aissa, S., Burgess, R.M., Busch, W., Creusot, N., Di Paolo, C., Escher, B.I., Hewitt, L.M., Hilscherova, K., Hollender, J., Hollert, H., Jonker, W., Kool, J., Lamoree, M., Muschket, M., Neumann, S., Rostkowski, P., Ruttkies, C., Schollee, J., Schymanski, E.L., Schulze, T., Seiler, T.-B., Tindall, A.J., De Aragão Umbuzeiro, G., Vrana, B., Krauss, M. (2016):
Effect-directed analysis supporting monitoring of aquatic environments — An in-depth overview
Sci. Total Environ. 544 , 1073 - 1118
full text (doi)
9849 Busch, W. (2010):
Toxicity of engineered nanoparticles towards vertebrate cells in vitro
Dissertation, Martin-Luther-Universität Halle-Wittenberg
PhD Dissertation 15/2010
Helmholtz-Zentrum für Umweltforschung - UFZ, Leipzig, 150 pp.
full text (url)
10728 Busch, W., Bastian, S., Trahorsch, U., Iwe, M., Kühnel, D., Meißner, T., Springer, A., Gelinsky, M., Richter, V., Ikonomidou, C., Potthoff, A., Lehmann, I., Schirmer, K. (2011):
Internalisation of engineered nanoparticles into mammalian cells in vitro: influence of cell type and particle properties
J. Nanopart. Res. 13 (1), 293 - 310
full text (doi)
11242 Busch, W., Duis, K., Fenske, M., Maack, G., Legler, J., Padilla, S., Strähle, U., Witters, H., Scholz, S. (2011):
The zebrafish embryo model in toxicology and teratology, September 2–3, 2010, Karlsruhe, Germany
Reprod. Toxicol. 31 (4), 585 - 588
full text (doi)
9848 Busch, W., Kühnel, D., Schirmer, K., Scholz, S. (2010):
Tungsten carbide cobalt nanoparticles exert hypoxia-like effects on the gene expression level in human keratinocytes
BMC Genomics 11 , art. 65
full text (doi)
103 Busch, W., Kühnel, D., Springer, A., Meissner, T., Gelinsky, M., Potthoff, A., Scholz, S., Richter, V., Schirmer, K. (2009):
Tungsten carbide and tungsten carbide cobalt nanoparticle toxicity: The role of cellular particle uptake, leached ions and cobalt bioavailability
Toxicol. Lett. 189 (Suppl. 1), S185 - S185
full text (doi)
17484 Busch, W., Schmidt, S., Kühne, R., Schulze, T., Krauss, M., Altenburger, R. (2016):
Micropollutants in European rivers: A mode of action survey to support the development of effect-based tools for water monitoring
Environ. Toxicol. Chem. 35 (8), 1887 - 1899
full text (doi)
12050 Büttner, A., Busch, W., Klüver, N., Giannis, A., Scholz, S. (2012):
Transcriptional responses of zebrafish embryos exposed to potential sonic hedgehog pathway interfering compounds deviate from expression profiles of cyclopamine
Reprod. Toxicol. 33 (2), 254 - 263
full text (doi)
22778 Canzler, S., Schor, J., Busch, W., Schubert, K., Rolle-Kampczyk, U.E., Seitz, H., Kamp, H., von Bergen, M., Buesen, R., Hackermüller, J. (2020):
Prospects and challenges of multi‑omics data integration in toxicology
Arch. Toxicol. 94 (2), 371 - 388
full text (doi)
22169 Drozdova, P., Rivarola-Duarte, L., Bedulina, D., Axenov-Gribanov, D., Schreiber, S., Gurkov, A., Shatilina, Z., Vereshchagina, K., Lubyaga, Y., Madyarova, E., Otto, C., Jühling, F., Busch, W., Jakob, L., Lucassen, M., Sartoris, F.J., Hackermüller, J., Hoffmann, S., Pörtner, H.-O., Luckenbach, T., Timofeyev, M., Stadler, P.F. (2019):
Comparison between transcriptomic responses to short-term stress exposures of a common Holarctic and endemic Lake Baikal amphipods
BMC Genomics 20 , art. 712
full text (doi)
14492 Ebert, C., Knoche, M., Geyer, S., Rödiger, T., Busch, W., Gloaguen, R., Pohl, E., Osenbrück, K., Baidulloeva, J., Weise, S.M. (2012):
Isotopic and hydrochemical characterisation of a (semi)-arid catchment in the Tajik Pamirs
EGU General Assembly 2012, Vienna, Austria, 22–27 April 2012
Geophysical Research Abstracts 14
European Geosciences Union (EGU), p. EGU2012-10834
14696 Escher, B.I., Allinson, M., Altenburger, R., Bain, P.A., Balaguer, P., Busch, W., Crago, J., Denslow, N.D., Dopp, E., Hilscherova, K., Humpage, A.R., Kumar, A., Grimaldi, M., Jayasinghe, B.S., Jarosova, B., Jia, A., Makarov, S., Maruya, K.A., Medvedev, A., Mehinto, A.C., Mendez, J.E., Poulsen, A., Prochazka, E., Richard, J., Schifferli, A., Schlenk, D., Scholz, S., Shiraishi, F., Snyder, S., Su, G., Tang, J.Y.M., van der Burg, B., van der Linden, S.C., Werner, I., Westerheide, S.D., Wong, C.K.C., Yang, M., Yeung, B.H.Y., Zhang, X., Leusch, F.D.L. (2014):
Benchmarking organic micropollutants in wastewater, recycled water and drinking water with in vitro bioassays
Environ. Sci. Technol. 48 (3), 1940 - 1956
full text (doi)
18200 Escher, B.I., Hackermüller, J., Polte, T., Scholz, S., Aigner, A., Altenburger, R., Böhme, A., Bopp, S.K., Brack, W., Busch, W., Chadeau-Hyam, M., Covaci, A., Eisenträger, A., Galligan, J.J., Garcia-Reyero, N., Hartung, T., Hein, M., Herberth, G., Jahnke, A., Kleinjans, J., Klüver, N., Krauss, M., Lamoree, M., Lehmann, I., Luckenbach, T., Miller, G.W., Müller, A., Phillips, D.H., Reemtsma, T., Rolle-Kampczyk, U., Schüürmann, G., Schwikowski, B., Tan, Y.-M., Trump, S., Walter-Rohde, S., Wambaugh, J.F. (2017):
From the exposome to mechanistic understanding of chemical-induced adverse effects
Environ. Int. 99 , 97 - 106
full text (doi)
23326 Jakobs, G., Krüger, J., Schüttler, A., Altenburger, R., Busch, W. (2020):
Mixture toxicity analysis in zebrafish embryo a time and concentration resolved study on mixture effect predictivity
Environ. Sci. Eur. 32 , art. 143
full text (doi)
11933 Klüver, N., Yang, L., Busch, W., Scheffler, K., Scheffler, P., Strähle, U., Scholz, S. (2011):
Transcriptional response of zebrafish embryos exposed to neurotoxic compounds reveals a muscle activity dependent hspb11 expression
PLoS One 6 (12), e29063
full text (doi)
22553 Krämer, S., Busch, W., Schüttler, A. (2020):
A self-organizing map of the fathead minnow liver transcriptome to identify consistent toxicogenomic patterns across chemical fingerprints
Environ. Toxicol. Chem. 39 (3), 526 - 537
full text (doi)
355 Kühnel, D., Busch, W., Meissner, T., Springer, A., Potthoff, A., Richter, V., Gelinsky, M., Scholz, S., Schirmer, K. (2009):
Agglomeration of tungsten carbide nanoparticles in exposure medium does not prevent uptake and toxicity toward a rainbow trout gill cell line
Aquat. Toxicol. 93 (2-3), 91 - 99
full text (doi)
12564 Kühnel, D., Scheffler, K., Wellner, P., Meißner, T., Potthoff, A., Busch, W., Springer, A., Schirmer, K. (2012):
Comparative evaluation of particle properties, formation of reactive oxygen species and genotoxic potential of tungsten carbide based nanoparticles in vitro
J. Hazard. Mater. 227-228 , 418 - 426
full text (doi)
19109 Kühnert, A., Vogs, C., Seiwert, B., Aulhorn, S., Altenburger, R., Hollert, H., Küster, E., Busch, W. (2017):
Biotransformation in the zebrafish embryo – temporal gene transcription changes of cytochrome P450 enzymes and internal exposure dynamics of the AhR binding xenobiotic benz[a]anthracene
Environ. Pollut. 230 , 1 - 11
full text (doi)
21229 Legradi, J.B., Di Paolo, C., Kraak, M.H.S., van der Geest, H.G., Schymanski, E.L., Williams, A.J., Dingemans, M.M.L., Massei, R., Brack, W., Cousin, X., Begout, M.-L., van der Oost, R., Carion, A., Suarez‑Ulloa, V., Silvestre, F., Escher, B.I., Engwall, M., Nilén, G., Keiter, S.H., Pollet, D., Waldmann, P., Kienle, C., Werner, I., Haigis, A.-C., Knapen, D., Vergauwen, L., Spehr, M., Schulz, W., Busch, W., Leuthold, D., Scholz, S., vom Berg, C.M., Basu, N., Murphy, C.A., Lampert, A., Kuckelkorn, J., Grummt, T., Hollert, H. (2018):
An ecotoxicological view on neurotoxicity assessment
Environ. Sci. Eur. 30 , art. 46
full text (doi)
21233 Leuthold, D., Klüver, N., Altenburger, R., Busch, W. (2019):
Can environmentally relevant neuroactive chemicals specifically be detected with the locomotor response test in zebrafish embryos?
Environ. Sci. Technol. 53 (1), 482 - 493
full text (doi)
16643 Luckenbach, T., Küster, E., Busch, W., Scholz, S., Altenburger, R. (2015):
What determines chemical uptake by the zebrafish embryo model?
Toxicol. Lett. 238 (2, Suppl.), S54
full text (doi)
19999 Massei, R., Busch, W., Wolschke, H., Schinkel, L., Bitsch, M., Schulze, T., Krauss, M., Brack, W. (2018):
Screening of pesticide and biocide patterns as risk drivers in sediments of major European river mouths: ubiquitous or river basin-specific contamination?
Environ. Sci. Technol. 52 (4), 2251 - 2260
full text (doi)
10294 Meissner, T., Kühnel, D., Busch, W., Oswald, S., Richter, V., Michaelis, A., Schirmer, K., Potthoff, A. (2010):
Physical-chemical characterization of tungsten carbide nanoparticles as a basis for toxicological investigations
Nanotoxicology 4 (2), 196 - 206
full text (doi)
19298 Neale, P.A., Altenburger, R., Aït-Aïssa, S., Brion, F., Busch, W., De Aragão Umbuzeiro, G., Denison, M.S., Du Pasquier, D., Hilscherová, K., Hollert, H., Morales, D.A., Novák, J., Schlichting, R., Seiler, T.-B., Serra, H., Shao, Y., Tindall, A.J., Tollefsen, K.E., Williams, T.D., Escher, B.I. (2017):
Development of a bioanalytical test battery for water quality monitoring: Fingerprinting identified micropollutants and their contribution to effects in surface water
Water Res. 123 , 734 - 750
full text (doi)
19929 Neale, P.A., Brack, W., Ait-Aissa, S., Busch, W., Hollender, J., Krauss, M., Maillot-Maréchal, E., Munz, N.A., Schlichting, R., Schulze, T., Vogler, B., Escher, B.I. (2018):
Solid-phase extraction as sample preparation of water samples for cell-based and other in vitro bioassays
Environ. Sci.-Proc. Imp. 20 (3), 493 - 504
full text (doi)
18079 Neale, P.A., Munz, N.A., Aїt-Aїssa, S., Altenburger, R., Brion, F., Busch, W., Escher, B.I., Hilscherová, K., Kienle, C., Novák, J., Seiler, T.-B., Shao, Y., Stamm, C., Hollender, J. (2017):
Integrating chemical analysis and bioanalysis to evaluate the contribution of wastewater effluent on the micropollutant burden in small streams
Sci. Total Environ. 576 , 785 - 795
full text (doi)
2137 Osenbrück, K., Gläser, H.-R., Knöller, K., Weise, S.M., Möder, M., Wennrich, R., Schirmer, M., Reinstorf, F., Busch, W., Strauch, G. (2007):
Sources and transport of selected organic micropollutants in urban groundwater underlying the city of Halle (Saale), Germany
Water Res. 41 (15), 3259 - 3270
full text (doi)
12799 Potthoff, A., Meißner, T., Richter, V., Busch, W., Kühnel, D., Bastian, S., Iwe, M., Springer, A. (2009):
Evaluation of health risks of nanoparticles - a contribution to a sustainable development of nanotechnology
In: Kny, E. (ed.)
Nanocomposite materials
Solid State Phenomena 151
Trans Tech Publications, Durnten-Zurich, p. 183 - 189
full text (doi)
3739 Römpler, H., Sangkuhl, K., Busch, W., Schöneberg, T., Schulz, A. (2005):
Structural evolution of the V2-receptor in mammals
Naunyn-Schmiedebergs Arch. Pharmacol. 371 (Suppl. 1), R15
3750 Sangkuhl, K., Römpler, H., Busch, W., Karges, B., Schöneberg, T. (2005):
Nephrogenic diabetes insipidus caused by mutation of Tyr205: A key residue of V2 vasopressin receptor function
Hum. Mutat. 25 (5), 505
full text (doi)
20211 Schmidt, S., Busch, W., Altenburger, R. (2017):
Biotestverfahren zur Abschätzung von Wirkpotenzialen in der aquatischen Umwelt : Vorschlag einer modularen Biotestbatterie für das aquatische Umweltmonitoring als Ergebnis einer systematischen Literaturrecherche und Bewertung
LUBW Landesanstalt für Umwelt Baden-Württemberg, Karlsruhe, 98 S.
17231 Schmidt, S., Busch, W., Altenburger, R., Küster, E. (2016):
Mixture toxicity of water contaminants-effect analysis using the zebrafish embryo assay (Danio rerio)
Chemosphere 152 , 503 - 512
full text (doi)
21907 Schüttler, A., Altenburger, R., Ammar, M., Bader-Blukott, M., Jakobs, G., Knapp, J., Krüger, J., Reiche, K., Wu, G.-M., Busch, W. (2019):
Map and model—moving from observation to prediction in toxicogenomics
GigaScience 8 (6), giz057
full text (doi)
24611 Schüttler, A., Jakobs, G., Fix, J.M., Krauss, M., Krüger, J., Leuthold, D., Altenburger, R., Busch, W. (2021):
Transcriptome-wide prediction and measurement of combined effects induced by chemical mixture exposure in zebrafish embryos
Environ. Health Perspect. 129 (4), art. 047006
full text (doi)
18633 Schüttler, A., Reiche, K., Altenburger, R., Busch, W. (2017):
The transcriptome of the zebrafish embryo after chemical exposure: a meta-analysis
Toxicol. Sci. 157 (2), 291 - 304
full text (doi)
21813 Serra, H., Scholze, M., Altenburger, R., Busch, W., Budzinski, H., Brion, F., Aït-Aïssa, S. (2019):
Combined effects of environmental xeno-estrogens within multi-component mixtures: Comparison of in vitro human- and zebrafish-based estrogenicity bioassays
Chemosphere 227 , 334 - 344
full text (doi)
22367 Shatilina, Z., Drozdova, P., Bedulina, D., Rivarola-Duarte, L., Schreiber, S., Otto, C., Jühling, F., Aulhorn, S., Busch, W., Lubyaga, Y., Kondrateva, E., Pobezhimova, T., Jakob, L., Lucassen, M., Sartoris, F.J., Hackermüller, J., Pörtner, H.-O., Stadler, P.F., Luckenbach, T., Timofeyev, M. (2020):
Transcriptome-level effects of the model organic pollutant phenanthrene and its solvent acetone in three amphipod species
Comp. Biochem. Physiol. D-Genomics Proteomics 33 , art. 100630
full text (doi)
16435 Smetanová, S., Riedl, J., Zitzkat, D.P., Altenburger, R., Busch, W. (2015):
High-throughput concentration–response analysis for omics datasets
Environ. Toxicol. Chem. 34 (9), 2167 - 2180
full text (doi)
10549 Stärk, H.-J., Kühnel, D., Busch, W., Wellner, P., Schirmer, C. (2010):
Charakterisierung der Aufnahme von Wolframkarbid-Nanopartikeln durch Humanzellen mittels LA-ICP-MS
In: Otto, M., Bulska, E., Knapp, G., Schlemmer, G., Ullrich, A., Welz, B., Wennrich, R. (Hrsg.)
CANAS '09 - Colloquium Analytische Atomspektroskopie, 22.-25. März 2009, Freiberg
TU Bergakademie Freiberg, Institut für Analytische Chemie, Freiberg, S. 44 - 44
21825 Weil, M., Mackenzie, K., Foit, K., Kühnel, D., Busch, W., Bundschuh, M., Schulz, R., Duis, K. (2019):
Environmental risk or benefit? Comprehensive risk assessment of groundwater treated with nano Fe0-based Carbo-Iron®
Sci. Total Environ. 677 , 156 - 166
full text (doi)
16217 Weil, M., Meißner, T., Busch, W., Springer, A., Kühnel, D., Schulz, R., Duis, K. (2015):
The oxidized state of the nanocomposite Carbo-Iron® causes no adverse effects on growth, survival and differential gene expression in zebrafish
Sci. Total Environ. 530-531 , 198 - 208
full text (doi)
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