Details zur Publikation

Kategorie Textpublikation
Referenztyp Zeitschriften
DOI 10.1078/S1438-4639(04)70002-4
Titel (primär) Helicobacter pylori prevalence in Leipzig's 1998 school entries: methodology and first results
Autor Krumbiegel, P.; Herbarth, O.; Fritz, G.J.; Schlink, U. ORCID logo ; Gutsmuths, F.-J.; Kindler, A.; Richter, T.
Quelle International Journal of Hygiene and Environmental Health
Erscheinungsjahr 2000
Band/Volume 203
Heft 1
Seite von 11
Seite bis 16
Sprache englisch
Keywords birth cohort; 13C breath test; environmental influence; epidemiology; Helicobacter pylori infection routes; 15N urine test; prevalence; questionnaire; school beginners

The non-invasive, stable-isotope-aided Helicobacter pylori (H. pylori) tests- breath and equivalent urine tests- were offered on a voluntary basis as part of the mandatory school entry medical examination to the 1998 school entry cohort of the City of Leipzig (480000 residents). Parents of participating subjects were asked to fill out a detailed epidemiologic questionnaire.

The response rate was 94% (n 2228 of 2369 school starters born in 1991/92). Parent-completed questionnaires were returned by 1890 (80%) children. The overall H. pylori positive prevalence was 7.2%. The prevalence among children with a test and a parent-completed questionnaire was 6.5%. Prevalences among subsequently tested family members of the positive tested children was 65,60 and 39% for mothers, fathers and siblings respectively. Though studies have shown that the direct transmission of the bacterium (oral- oral and fecal- oral) is a dominant pathway of infection, the questionnaire analyses indicate associations between H. pylori colonisation and living as well as environmental conditions.

dauerhafte UFZ-Verlinkung
Krumbiegel, P., Herbarth, O., Fritz, G.J., Schlink, U., Gutsmuths, F.-J., Kindler, A., Richter, T. (2000):
Helicobacter pylori prevalence in Leipzig's 1998 school entries: methodology and first results
Int. J. Hyg. Environ. Health. 203 (1), 11 - 16 10.1078/S1438-4639(04)70002-4