Details zur Publikation |
| Kategorie | Textpublikation |
| Referenztyp | Zeitschriften |
| DOI | 10.1016/S0925-4439(00)00038-7 |
| Titel (primär) | Structure of tau protein and assembly into paired helical filaments |
| Autor | Friedhoff, P.; von Bergen, M.; Mandelkow, E.-M.; Mandelkow, E. |
| Quelle | Biochimica et Biophysica Acta-Molecular Basis of Disease |
| Erscheinungsjahr | 2000 |
| Department | PROTEOM |
| Band/Volume | 1502 |
| Heft | 1 |
| Seite von | 122 |
| Seite bis | 132 |
| Sprache | englisch |
| Keywords | Alzheimer's disease; Paired helical filament; Tau protein; Self-assembly; Nucleation |
| Abstract | Over the past few years the systematic investigation of paired helical filament assembly from tau protein in vitro has become feasible. We review our current understanding of the structure and conformations of tau protein and how this affects tau's assembly into the pathological paired helical filaments in Alzheimer's disease. |
| dauerhafte UFZ-Verlinkung | https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=7140 |
| Friedhoff, P., von Bergen, M., Mandelkow, E.-M., Mandelkow, E. (2000): Structure of tau protein and assembly into paired helical filaments Biochim. Biophys. Acta-Mol. Basis Dis. 1502 (1), 122 - 132 10.1016/S0925-4439(00)00038-7 |
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