Details zur Publikation

Referenztyp Zeitschriften
DOI / URL Link
Titel (primär) Structure of tau protein and assembly into paired helical filaments
Autor Friedhoff, P.; von Bergen, M.; Mandelkow, E.-M.; Mandelkow, E.;
Journal / Serie Biochimica et Biophysica Acta-Molecular Basis of Disease
Erscheinungsjahr 2000
Department PROTEOM;
Band/Volume 1502
Heft 1
Sprache englisch;
Keywords Alzheimer's disease; Paired helical filament; Tau protein; Self-assembly; Nucleation
Abstract Over the past few years the systematic investigation of paired helical filament assembly from tau protein in vitro has become feasible. We review our current understanding of the structure and conformations of tau protein and how this affects tau's assembly into the pathological paired helical filaments in Alzheimer's disease.
ID 7140
dauerhafte UFZ-Verlinkung https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=7140
Friedhoff, P., von Bergen, M., Mandelkow, E.-M., Mandelkow, E. (2000):
Structure of tau protein and assembly into paired helical filaments
Biochim. Biophys. Acta-Mol. Basis Dis. 1502 (1), 122 - 132