Details zur Publikation

Kategorie Textpublikation
Referenztyp Zeitschriften
DOI 10.1007/s00253-002-1042-4
Volltext Shareable Link
Titel (primär) Inhibition of lotic biofilms by Diclofenac
Autor Paje, M.L.F.; Kuhlicke, U.; Winkler, M.; Neu, T.R.
Quelle Applied Microbiology and Biotechnology
Erscheinungsjahr 2002
Department FLOEK
Band/Volume 59
Heft 4-5
Seite von 488
Seite bis 492
Sprache englisch
Abstract Diclofenac, a common drug, was subjected to degradation studies using river biofilms grown in rotating annular reactors. Degradation of diclofenac was possible after acclimatisation as confirmed by liquid chromatography-mass spectrometry analyses. Adapted biofilms showed that degradation down to 10–25% of the initial concentration could be achieved within 4 days. In situ observation by confocal laser scanning microscopy, however, revealed slow biofilm development in the presence of diclofenac compared with control experiments grown in river water only. This was substantiated by low cell counts and isolation of fewer kinds of microorganisms from diclofenac-grown biofilms. Fluorescent in situ hybridisation analyses confirmed the presence of various bacterial groups, especially those belonging to the Cytophaga-Flavobacterium and γ-Proteobacteria groups, in the biofilms. Quantification of image data indicated a negative effect of diclofenac on the growth of bacteria and algae. This is the first report on degradation of diclofenac by lotic biofilms.
dauerhafte UFZ-Verlinkung https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=5886
Paje, M.L.F., Kuhlicke, U., Winkler, M., Neu, T.R. (2002):
Inhibition of lotic biofilms by Diclofenac
Appl. Microbiol. Biotechnol. 59 (4-5), 488 - 492 10.1007/s00253-002-1042-4