Details zur Publikation

Referenztyp Zeitschriften
DOI / URL Link
Titel (primär) Auxofuran, a novel metabolite that stimulates the growth of fly agaric, is produced by the mycorrhiza helper bacterium Streptomyces strain AcH 505
Autor Riedlinger, J.; Schrey, S.D.; Tarkka, M.T.; Hampp, R.; Kapur, M.; Fiedler, H.P.;
Journal / Serie Applied and Environmental Microbiology
Erscheinungsjahr 2006
Department BOOEK;
Band/Volume 72
Heft 5
Sprache englisch;
Abstract The mycorrhiza helper bacterium Streptomyces strain AcH 505 improves mycelial growth of ectomycorrhizal fungi and formation of ectomycorrhizas between Amanita muscaria and spruce but suppresses the growth of plant-pathogenic fungi, suggesting that it produces both fungal growth-stimulating and -suppressing compounds. The dominant fungal-growth-promoting substance produced by strain AcH 505, auxoforan, was isolated, and its effect on the levels of gene expression of A. muscaria was investigated. Auxofuran and its synthetic analogue 7-dehydroxy-auxofuran were most effective at a concentration of 15 mu M, and application of these compounds led to increased lipid metabolism-related gene expression. Cocultivation of strain AcH 505 and A. muscaria stimulated auxofuran production by the streptomycete. The antifungal substances produced by strain AcH 505 were identified as the antibiotics WS-5995 B and C. WS-5995 B completely blocked mycelial growth at a concentration of 60 mu M and caused a cell stress-related gene expression response in A. muscaria. Characterization of these compounds provides the foundation for molecular analysis of the fungus-bacterium interaction in the ectomycorrhizal symbiosis between fly agaric and spruce.
ID 2946
dauerhafte UFZ-Verlinkung https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=2946
Riedlinger, J., Schrey, S.D., Tarkka, M.T., Hampp, R., Kapur, M., Fiedler, H.P. (2006):
Auxofuran, a novel metabolite that stimulates the growth of fly agaric, is produced by the mycorrhiza helper bacterium Streptomyces strain AcH 505
Appl. Environ. Microb. 72 (5), 3550 - 3557