Details zur Publikation |
Kategorie | Textpublikation |
Referenztyp | Zeitschriften |
DOI | 10.1080/00211919208050831 |
Titel (primär) | 15N NMR of glycine metabolism in liver, muscle and kidney of rats using a new pulsed overhauser technique (POE) |
Autor | Gründer, W.; Krumbiegel, P.; Gersonde, K. |
Quelle | Isotopenpraxis |
Erscheinungsjahr | 1992 |
Department | ISOBIO; EXPOEPID |
Band/Volume | 28 |
Heft | 1 |
Seite von | 81 |
Seite bis | 84 |
Sprache | englisch |
Keywords | Diagnostic techniques, glycine, metabolism, nitrogen 15, nuclear magnetic resonance spectroscopy, Overhauser techniques, rats |
Abstract | Following intravenous injections of ["N]glycine (97 at.% "N, 4Wmg in 1.5 ml isotonic saline) to Lewis rzts several organs were excised. The time courses of the "N NMR spectral (40.55 MHz) were measured at 37°C after cold (4°C) or warm (37°C) storage. The application of the Ovcrhauser POE technique yielded signal enhancement by a factor of -2.7 and -1.3 in sceletal and heart muscle, respectively, at 37"C, but no enhancement in liver and kidney. In the time course of liver measurements at 37°C. intermediate metabolic products of glycinc were observed, such as serine, glutamine, alanine, and tryptophane |
dauerhafte UFZ-Verlinkung | https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=27741 |
Gründer, W., Krumbiegel, P., Gersonde, K. (1992): 15N NMR of glycine metabolism in liver, muscle and kidney of rats using a new pulsed overhauser technique (POE) Isotopenpraxis 28 (1), 81 - 84 10.1080/00211919208050831 |