Details zur Publikation

Kategorie Textpublikation
Referenztyp Zeitschriften
DOI 10.1080/00211919208050831
Titel (primär) 15N NMR of glycine metabolism in liver, muscle and kidney of rats using a new pulsed overhauser technique (POE)
Autor Gründer, W.; Krumbiegel, P.; Gersonde, K.
Quelle Isotopenpraxis
Erscheinungsjahr 1992
Department ISOBIO; EXPOEPID
Band/Volume 28
Heft 1
Seite von 81
Seite bis 84
Sprache englisch
Keywords Diagnostic techniques, glycine, metabolism, nitrogen 15, nuclear magnetic resonance spectroscopy, Overhauser techniques, rats
Abstract Following intravenous injections of ["N]glycine (97 at.% "N, 4Wmg in 1.5 ml isotonic saline) to Lewis rzts  several organs were excised. The time courses of the "N NMR spectral (40.55 MHz) were measured at 37°C after cold (4°C) or warm (37°C) storage. The application of the Ovcrhauser POE technique yielded  signal enhancement by  a factor of -2.7 and -1.3 in sceletal and heart muscle, respectively, at 37"C, but no enhancement in liver and kidney. In the time course of liver measurements at 37°C. intermediate  metabolic products of glycinc were observed, such as serine, glutamine, alanine, and tryptophane
dauerhafte UFZ-Verlinkung https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=27741
Gründer, W., Krumbiegel, P., Gersonde, K. (1992):
15N NMR of glycine metabolism in liver, muscle and kidney of rats using a new pulsed overhauser technique (POE)
Isotopenpraxis 28 (1), 81 - 84 10.1080/00211919208050831