Details zur Publikation

Kategorie Textpublikation
Referenztyp Zeitschriften
DOI 10.1021/acs.est.2c04345
Titel (primär) Time between sequential exposures to multiple stress turns antagonism into synergism
Autor Schunck, F.; Liess, M.
Quelle Environmental Science & Technology
Erscheinungsjahr 2022
Department OEKOTOX
Band/Volume 56
Heft 20
Seite von 14660
Seite bis 14667
Sprache englisch
Topic T9 Healthy Planet
Keywords multiple stress; interactions; pesticides; model; daphnia; risk assessment; sequential exposure
Abstract Aquatic communities are exposed to repeated pulses of toxicants and environmental stressors. We hypothesize that the dose, order, and timing of stress events shape the interactions of these communities. For this, we conducted a fully-crossed, four-factorial, multiple stress exposure experiment to study the combined effects of Esfenvalerate and ultraviolet-B (UV-B) radiation related to the exposure timing and order on Daphnia magna. We revealed that initial exposure to low stress doses, independent of the stress type (UV-B or Esfenvalerate), significantly increased the resistance toward the second stressor. This beneficial effect was apparent only when the second stressor was applied immediately after the first stressor (p < 0.01). When the period between stressor applications was extended to 2 days, the antagonism between the two stressors turned into synergism. The stressor interaction could be predicted with an abstract-mechanistic model of the temporal dynamics of the early-stage stress response. With this model, the timing and order of exposures were able to successfully explain interactions observed in all treatments (model-R2 = 1.0). We conclude that especially the duration of a break between exposures and the exposure dose have a decisive influence on interactions between toxicants and environmental stressors.
dauerhafte UFZ-Verlinkung
Schunck, F., Liess, M. (2022):
Time between sequential exposures to multiple stress turns antagonism into synergism
Environ. Sci. Technol. 56 (20), 14660 - 14667 10.1021/acs.est.2c04345