Details zur Publikation |
| Kategorie | Textpublikation |
| Referenztyp | Buchkapitel |
| DOI | 10.1016/B978-0-323-89773-0.00013-8 |
| Titel (primär) | Using zebrafish to assess developmental neurotoxicity |
| Titel (sekundär) | Reproductive and developmental toxicology. Third edition |
| Autor | Padilla, S.; Hill, B.N.; Legradi, J.; Klüver, N. |
| Herausgeber | Gupta, R.C. |
| Erscheinungsjahr | 2022 |
| Department | BIOTOX |
| Seite von | 239 |
| Seite bis | 251 |
| Sprache | englisch |
| Topic | T9 Healthy Planet |
| Keywords | Alternative model; Developmental; Ecotoxicity; Neurotoxicity; Screening; Zebrafish |
| Abstract | It is widely accepted that the developing nervous system is especially vulnerable to a variety of chemicals, including drugs and environmental contaminants; however our understanding of the risks from chemical exposures during development is rudimentary. Zebrafish have become a popular test species in toxicology, pharmacology, and biomedical research. This chapter was written as an introduction to the use of zebrafish in developmental neurotoxicology, and to encourage the use of this model either for human or ecological risk characterizations. We have endeavored to make the reader aware of significant research findings, and to offer a balanced view of the advantages and limitations in using zebrafish as a model for investigating developmental neurotoxicity. |
| dauerhafte UFZ-Verlinkung | https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=25803 |
| Padilla, S., Hill, B.N., Legradi, J., Klüver, N. (2022): Using zebrafish to assess developmental neurotoxicity In: Gupta, R.C. (ed.) Reproductive and developmental toxicology. Third edition Academic Press / Elsevier, London, p. 239 - 251 10.1016/B978-0-323-89773-0.00013-8 |
|