Details zur Publikation

Kategorie Textpublikation
Referenztyp Zeitschriften
DOI 10.1016/j.copbio.2023.102892
Volltext Akzeptiertes Manuskript
Titel (primär) Cyanobacteria as whole-cell factories: current status and future prospectives
Autor Toepel, J.; Karande, R.; Klähn, S.; Bühler, B.
Quelle Current Opinion in Biotechnology
Erscheinungsjahr 2023
Department UMB; SOMA
Band/Volume 80
Seite von art. 102892
Sprache englisch
Topic T7 Bioeconomy
Abstract Cyanobacteria as phototrophic microorganisms bear great potential to produce chemicals from sustainable resources such as light and CO2. Most studies focus on either strain engineering or tackling metabolic constraints. Recently gained knowledge on internal electron and carbon fluxes and their regulation provides new opportunities to efficiently channel cellular resources toward product formation. Concomitantly, novel photobioreactor concepts are developed to ensure sufficient light supply. This review summarizes the newest developments in the field of cyanobacterial engineering to finally establish photosynthesis-based production processes. A holistic approach tackling genetic, metabolic, and biochemical engineering in parallel is considered essential to turn their application into an ecoefficient and economically feasible option for a future green bioeconomy.
dauerhafte UFZ-Verlinkung
Toepel, J., Karande, R., Klähn, S., Bühler, B. (2023):
Cyanobacteria as whole-cell factories: current status and future prospectives
Curr. Opin. Biotechnol. 80 , art. 102892 10.1016/j.copbio.2023.102892