Details zur Publikation |
| Kategorie | Textpublikation |
| Referenztyp | Zeitschriften |
| DOI | 10.3390/ijms221910824 |
Lizenz  |
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| Titel (primär) | The role of GPR15 function in blood and vasculature |
| Autor | Bauer, M. |
| Quelle | International Journal of Molecular Sciences |
| Erscheinungsjahr | 2021 |
| Department | IMMU |
| Band/Volume | 22 |
| Heft | 19 |
| Seite von | art. 10824 |
| Sprache | englisch |
| Topic | T9 Healthy Planet |
| Keywords | GPR15; C10orf99; thrombomodulin; lymphocyte; blood; endothelial cell; vasculature |
| Abstract | Since the first prominent description of the orphan G protein-coupled receptor 15 (GPR15) on lymphocytes as a co-receptor for the human immunodeficiency virus (HIV) type 1 and 2 and the first report about the GPR15-triggered cytoprotective effect on vascular endothelial cells by recombinant human thrombomodulin, several decades passed before the GPR15 has been recently deorphanized. Because of new findings on GPR15, this review will summarize the consequences of GPR15 signaling considering the variety of GPR15-expressing cell types and of GPR15 ligands, with a focus on blood and vasculature. |
| dauerhafte UFZ-Verlinkung | https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=25205 |
| Bauer, M. (2021): The role of GPR15 function in blood and vasculature Int. J. Mol. Sci. 22 (19), art. 10824 10.3390/ijms221910824 |
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