Details zur Publikation

Kategorie Textpublikation
Referenztyp Zeitschriften
DOI 10.1002/elsc.202200039
Lizenz creative commons licence
Titel (primär) Membrane inlet-ion mobility spectrometry with automatic spectra evaluation as online monitoring tool for the process control of microalgae cultivation
Autor Cämmerer, M.; Mayer, T.; Schott, C.; Steingroewer, J.; Petrich, R.; Borsdorf, H. ORCID logo
Quelle Engineering in Life Sciences
Erscheinungsjahr 2023
Department MET
Band/Volume 23
Heft 4
Seite von e2200039
Sprache englisch
Topic T5 Future Landscapes
Supplements https://onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1002%2Felsc.202200039&file=elsc1555-sup-0001-SuppMat.docx
Keywords algal biotechnology; classification methods; ion mobility spectrometry; Limnospira platensis; process monitoring
Abstract The cultivation of algae either in open raceway ponds or in closed bioreactors could allow the renewable production of biomass for food, pharmaceutical, cosmetic, or chemical industries. Optimal cultivation conditions are however required to ensure that the production of these compounds is both efficient and economical. Therefore, high-frequency analytical measurements are required to allow timely process control and to detect possible disturbances during algae growth. Such analytical methods are only available to a limited extent. Therefore, we introduced a method for monitoring algae release volatile organic compounds (VOCs) in the headspace above a bioreactor in real time. This method is based on ion mobility spectrometry (IMS) in combination with a membrane inlet (MI). The unique feature of IMS is that complete spectra are detected in real time instead of sum signals. These spectral patterns produced in the ion mobility spectrum were evaluated automatically via principal component analysis (PCA). The detected peak patterns are characteristic for the respective algae culture; allow the assignment of the individual growth phases and reflect the influence of experimental parameters. These results allow for the first time a continuous monitoring of the algae cultivation and thus an early detection of possible disturbances in the biotechnological process.
dauerhafte UFZ-Verlinkung https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=24557
Cämmerer, M., Mayer, T., Schott, C., Steingroewer, J., Petrich, R., Borsdorf, H. (2023):
Membrane inlet-ion mobility spectrometry with automatic spectra evaluation as online monitoring tool for the process control of microalgae cultivation
Eng. Life Sci. 23 (4), e2200039 10.1002/elsc.202200039