Details zur Publikation

Kategorie Textpublikation
Referenztyp Zeitschriften
DOI 10.1016/
Titel (primär) Environmental factors and host microbiomes shape host–pathogen dynamics
Autor Bernardo-Cravo, A.P.; Schmeller, D.S.; Chatzinotas, A.; Vredenburg, V.T.; Loyau, A.
Quelle Trends in Parasitology
Erscheinungsjahr 2020
Department UMB; iDiv
Band/Volume 36
Heft 7
Seite von 616
Seite bis 633
Sprache englisch
Keywords parasite; fungi; Anthropocene; disease triangle; habitat degradation; disease pyramid
Abstract Microorganisms are increasingly recognized as ecosystem-relevant components because they affect the population dynamics of hosts. Functioning at the interface of the host and pathogen, skin and gut microbiomes are vital components of immunity. Recent work reveals a strong influence of biotic and abiotic environmental factors (including the environmental microbiome) on disease dynamics, yet the importance of the host–host microbiome–pathogen–environment interaction has been poorly reflected in theory. We use amphibians and the disease chytridiomycosis caused by the fungal pathogen Batrachochytrium dendrobatidis to show how interactions between host, host microbiome, pathogen, and the environment all affect disease outcome. Our review provides new perspectives that improve our understanding of disease dynamics and ecology by incorporating environmental factors and microbiomes into disease theory.
dauerhafte UFZ-Verlinkung
Bernardo-Cravo, A.P., Schmeller, D.S., Chatzinotas, A., Vredenburg, V.T., Loyau, A. (2020):
Environmental factors and host microbiomes shape host–pathogen dynamics
Trends Parasitol. 36 (7), 616 - 633 10.1016/