Details zur Publikation

Kategorie Textpublikation
Referenztyp Zeitschriften
DOI 10.1016/j.tcb.2019.12.007
Volltext Akzeptiertes Manuskript
Titel (primär) Subcellular chemical imaging: New avenues in cell biology
Autor Decelle, J.; Veronesi, G.; Gallet, B.; Stryhanyuk, H.; Benettoni, P.; Schmidt, M.; Tucoulou, R.; Passarelli, M.; Bohic, S.; Clode, P.; Musat, N.
Quelle Trends in Cell Biology
Erscheinungsjahr 2020
Department ISOBIO
Band/Volume 30
Heft 3
Seite von 173
Seite bis 188
Sprache englisch
Keywords chemical imaging; correlative microscopy; electron microscopy; elemental imaging; X-ray fluorescence; SIMS
UFZ Querschnittsthemen ProVIS;
Abstract To better understand the physiology and acclimation capability of the cell, one of the great challenges of the future is to access the interior of a cell and unveil its chemical landscape (composition and distribution of elements and molecules). Chemical imaging has greatly improved in sensitivity and spatial resolution to visualize and quantify nutrients, metabolites, toxic elements, and drugs in single cells at the subcellular level. This review aims to present the current potential of these emerging imaging technologies and to guide biologists towards a strategy for interrogating biological processes at the nanoscale. We also describe various solutions to combine multiple imaging techniques in a correlative way and provide perspectives and future directions for integrative subcellular imaging across different disciplines.
dauerhafte UFZ-Verlinkung
Decelle, J., Veronesi, G., Gallet, B., Stryhanyuk, H., Benettoni, P., Schmidt, M., Tucoulou, R., Passarelli, M., Bohic, S., Clode, P., Musat, N. (2020):
Subcellular chemical imaging: New avenues in cell biology
Trends Cell Biol. 30 (3), 173 - 188 10.1016/j.tcb.2019.12.007