Details zur Publikation |
| Kategorie | Textpublikation |
| Referenztyp | Zeitschriften |
| DOI | 10.1093/ajcn/85.2.530 |
| Titel (primär) | Maternal diet during pregnancy in relation to eczema and allergic sensitization in the offspring at 2 y of age |
| Autor | Sausenthaler, S.; Koletzko, S.; Schaaf, B.; Lehmann, I.; Borte, M.; Herbarth, O.; von Berg, A.; Wichmann, H.-E.; Heinrich, J. |
| Quelle | American Journal of Clinical Nutrition |
| Erscheinungsjahr | 2007 |
| Department | IMMU; EXPOEPID |
| Band/Volume | 85 |
| Heft | 2 |
| Seite von | 530 |
| Seite bis | 537 |
| Sprache | englisch |
| Keywords | Maternal diet; pregnancy; allergic diseases; children |
| Abstract | Background:Maternal diet during pregnancy might be one of the factors that influences fetal immune responses associated with childhood allergy. Objective:We analyzed the association between maternal diet during the last 4 wk of pregnancy and allergic sensitization and eczema in the offspring at 2 y of age. Design:Data from 2641 children at 2 y of age were analyzed within a German prospective birth cohort study (LISA). Maternal diet during the last 4 wk of pregnancy was assessed with a semiquantitative food-frequency questionnaire, which was administered shortly after childbirth. Results:High maternal intake of margarine [adjusted odds ratio (aOR): 1. 49; 95% CI: 1.08, 2.04] and vegetable oils (aOR: 1.48; 95% CI: 1.14, 1.91) during the last 4 wk of pregnancy was positively associated and high maternal fish intake (aOR: 0.75; 95% CI: 0.57, 0.98) was inversely associated with eczema during the first 2 y in the offspring. High celery (aOR: 1.85; 95% CI: 1.18, 2.89) and citrus fruit (aOR: 1.73; 95% CI: 1.18, 2.53) intakes increased the risk of sensitization against food allergens. In turn, sensitization against inhalant allergens was positively related to a high maternal intake of deep-frying vegetable fat (aOR: 1.61; 95% CI: 1.02, 2.54), raw sweet pepper (aOR: 2.16; 95% CI: 1.20, 3.90), and citrus fruit (aOR: 1.72; 95% CI: 1.02, 2.92). Conclusions:We suggest that the intake of allergenic foods and foods rich in n-6 polyunsaturated fatty acids during pregnancy may increase and foods rich in n-3 polyunsaturated fatty acids may decrease the risk of allergic diseases in the offspring. |
| dauerhafte UFZ-Verlinkung | https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=2240 |
| Sausenthaler, S., Koletzko, S., Schaaf, B., Lehmann, I., Borte, M., Herbarth, O., von Berg, A., Wichmann, H.-E., Heinrich, J. (2007): Maternal diet during pregnancy in relation to eczema and allergic sensitization in the offspring at 2 y of age Am. J. Clin. Nutr. 85 (2), 530 - 537 10.1093/ajcn/85.2.530 |
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