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Details zur Publikation

Referenztyp Zeitschriften
DOI / URL Link
Titel (primär) Evolution of fungal U3 snoRNAs: Structural variation and introns
Autor Canzler, S.; Stadler, P.F.; Hertel, J.;
Journal / Serie Non-Coding RNA
Erscheinungsjahr 2017
Department MOLSYB;
Band/Volume 3
Heft 1
Sprache englisch;
POF III (gesamt) F11;
Keywords small nucleolar RNA; pre-rRNA processing; RNA secondary structure; spliceosomal introns; RNA–RNA interactions; evolution
Abstract The U3 small nucleolar RNA (snoRNA) is an essential player in the initial steps of ribosomal RNA biogenesis which is ubiquitously present in Eukarya. It is exceptional among the small nucleolar RNAs in its size, the presence of multiple conserved sequence boxes, a highly conserved secondary structure core, its biogenesis as an independent gene transcribed by polymerase III, and its involvement in pre-rRNA cleavage rather than chemical modification. Fungal U3 snoRNAs share many features with their sisters from other eukaryotic kingdoms but differ from them in particular in their 5’ regions, which in fungi has a distinctive consensus structure and often harbours introns. Here we report on a comprehensive homology search and detailed analysis of the evolution of sequence and secondary structure features covering the entire kingdom Fungi.
ID 21393
dauerhafte UFZ-Verlinkung https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=21393
Canzler, S., Stadler, P.F., Hertel, J. (2017):
Evolution of fungal U3 snoRNAs: Structural variation and introns
Non-Coding RNA 3 (1), art. 3