Details zur Publikation

Referenztyp Zeitschriften
DOI / URL Link
Titel (primär) Handgrip strength is associated with improved spirometry in adolescents
Autor Phillips Smith, M.; Standl, M.; Berdel, D.; von Berg, A.; Bauer, C.-P.; Schikowski, T.; Koletzko, S.; Lehmann, I.; Krämer, U.; Heinrich, J.; Schulz, H.;
Journal / Serie PLOS ONE
Erscheinungsjahr 2018
Department IMMU;
Band/Volume 13
Heft 4
Sprache englisch;
POF III (gesamt) F11;
Supplements https://doi.org/10.1371/journal.pone.0194560.s001
https://doi.org/10.1371/journal.pone.0194560.s002
Abstract

Introduction

Pulmonary rehabilitation, including aerobic exercise and strength training, improves function, such as spirometric indices, in lung disease. However, we found spirometry did not correlate with physical activity (PA) in healthy adolescents (Smith ERJ: 42(4), 2016). To address whether muscle strength did, we measured these adolescents’ handgrip strength and correlated it with spirometry.

Methods

In 1846 non-smoking, non-asthmatic Germans (age 15.2 years, 47% male), we modeled spirometric indices as functions of handgrip strength by linear regression in each sex, corrected for factors including age, height, and lean body mass.

Results

Handgrip averaged 35.4 (SD 7.3) kg in boys, 26.6 (4.2) in girls. Spirometric volumes and flows increased linearly with handgrip. In boys each kg handgrip was associated with about 28 mL greater FEV1 and FVC; 60 mL/sec faster PEF; and 38 mL/sec faster FEF2575. Effects were 10–30% smaller in girls (all p<0.0001) and stable when Z-scores for spirometry and grip were modeled, after further correction for environment and/or other exposures, and consistent across stages of puberty.

Conclusions

Grip strength was associated with spirometry in a cohort of healthy adolescents whose PA was not. Thus, research into PA’s relationship with lung function should consider strength as well as total PA. Strength training may benefit healthy lungs; interventions are needed to prove causality.

ID 20296
dauerhafte UFZ-Verlinkung http://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=20296
Phillips Smith, M., Standl, M., Berdel, D., von Berg, A., Bauer, C.-P., Schikowski, T., Koletzko, S., Lehmann, I., Krämer, U., Heinrich, J., Schulz, H. (2018):
Handgrip strength is associated with improved spirometry in adolescents
PLOS One 13 (4), e0194560