Details zur Publikation

Kategorie Textpublikation
Referenztyp Zeitschriften
DOI 10.1016/j.envpol.2017.01.062
Titel (primär) Model-predicted occurrence of multiple pharmaceuticals in Swedish surface waters and their flushing to the Baltic Sea
Autor Lindim, C.; van Gils, J.; Cousins, I.T.; Kühne, R. ORCID logo ; Georgieva, D.; Kutsarova, S.; Mekenyan, O.
Quelle Environmental Pollution
Erscheinungsjahr 2017
Department OEC
Band/Volume 223
Seite von 590
Seite bis 604
Sprache englisch
Keywords Pharmaceuticals contamination; Baltic sea; Swedish rivers; Modelling; STREAM-EU
UFZ Querschnittsthemen RU3;
Abstract An exposure assessment for multiple pharmaceuticals in Swedish surface waters was made using the STREAM-EU model. Results indicate that Metformin (27 ton/y), Paracetamol (6.9 ton/y) and Ibuprofen (2.33 ton/y) were the drugs with higher amounts reaching the Baltic Sea in 2011. 35 of the studied substances had more than 1 kg/y of predicted flush to the sea. Exposure potential given by the ratio amount of the drug exported to the sea/amount emitted to the environment was higher than 50% for 7 drugs (Piperacillin, Lorazepam, Metformin, Hydroxycarbamide, Hydrochlorothiazide, Furosemide and Cetirizine), implying that a high proportion of them will reach the sea, and below 10% for 27 drugs, implying high catchment attenuation. Exposure potentials were found to be dependent of persistency and hydrophobicity of the drugs. Chemicals with Log D > 2 had exposure potentials <10% regardless of their persistence. Chemicals with Log D  <  −2 had exposure potentials >35% with higher ratios typically achieved for longer half-lives. For Stockholm urban area, 17 of the 54 pharmaceuticals studied had calculated concentrations higher than 10 ng/L. Model agreement with monitored values had an r2 = 0.62 for predicted concentrations and an r2 = 0.95 for predicted disposed amounts to sea.
dauerhafte UFZ-Verlinkung https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=18483
Lindim, C., van Gils, J., Cousins, I.T., Kühne, R., Georgieva, D., Kutsarova, S., Mekenyan, O. (2017):
Model-predicted occurrence of multiple pharmaceuticals in Swedish surface waters and their flushing to the Baltic Sea
Environ. Pollut. 223 , 590 - 604 10.1016/j.envpol.2017.01.062