Details zur Publikation

Kategorie Textpublikation
Referenztyp Zeitschriften
DOI 10.1016/j.bioelechem.2006.07.013
Titel (primär) Interaction of tin(II) and arsenic(III) with DNA at the nanostructure film modified electrodes
Autor Ferancová, A.; Adamovski, M.; Gründler, P.; Zima, J.; Barek, J.; Mattusch, J.; Wennrich, R.; Labuda, J.
Quelle Bioelectrochemistry
Erscheinungsjahr 2007
Department ANA
Band/Volume 71
Heft 1
Seite von 33
Seite bis 37
Sprache englisch
Keywords Tin; Arsenic; DNA damage; DNA biosensor; Voltammetry
Abstract Biosensors based on DNA and DNA-carbon nanotubes film immobilized at the surface of a screen-printed carbon electrode were used for simple in vitro tests of chemical toxicity. The damage to DNA caused by tin(II) and arsenic(III) compounds as components of specific reaction media was evaluated by means of an electrochemical DNA marker, [Co(phen)3]3+, as the portion of original dsDNA which survives an incubation of the biosensor in the cleavage medium. The results were confirmed by the electrically heated electrode and by the measurement of the DNA guanine moiety signal.
dauerhafte UFZ-Verlinkung https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=1753
Ferancová, A., Adamovski, M., Gründler, P., Zima, J., Barek, J., Mattusch, J., Wennrich, R., Labuda, J. (2007):
Interaction of tin(II) and arsenic(III) with DNA at the nanostructure film modified electrodes
Bioelectrochemistry 71 (1), 33 - 37 10.1016/j.bioelechem.2006.07.013