Details zur Publikation

Referenztyp Berichte
DOI / URL Link
Titel (primär) flowCHIC: Analyze flow cytometric data using histogram information R package version 1.0.0 http://www.bioconductor.org/packages/release/bioc/html/flowCHIC.html October 2014: 5 downloads (distinct IPs: ~500)
Autor Schumann, J.; Koch, C.; Günther, S.; Fetzer, I.; Müller, S.;
Erscheinungsjahr 2014
Department UMB;
Sprache englisch;
POF III (gesamt) R31;
Abstract CHIC means cytometric histogram image comparison and is a tool for evaluation of cytometric
datasets nearly automatically and very fast. CHIC neither requires gate setting procedures nor relies
on quanti cation and binning of event distributions within histograms. The evaluation of histograms
using CHIC is based on the main idea that histograms are converted into images thus working person
independent and with low computational demand. Although cell speci c information is given up in
this way it allows, on the other hand, huge datasets to be evaluated within very short time frames.
It is, therefore, a tool to visualize cell population or community dynamics and to suggest causes of
dynamic variations. The sensitivity of this technique was found to discriminate down to 0.5% internal
variation. On the rst hand it was developed for evaluation of cytometric microbial community data
but it can also be used for any other cytometric dataset.
ID 15751
dauerhafte UFZ-Verlinkung http://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=15751
Schumann, J., Koch, C., Günther, S., Fetzer, I., Müller, S. (2014):
flowCHIC: Analyze flow cytometric data using histogram information
R package version 1.0.0
http://www.bioconductor.org/packages/release/bioc/html/flowCHIC.html
October 2014: 5 downloads (distinct IPs: ~500)