Details zur Publikation

Kategorie Textpublikation
Referenztyp Zeitschriften
DOI 10.1016/j.chemosphere.2013.12.093
Titel (primär) Nonextractable residue formation of sulfonamide antimicrobials: New insights from soil incubation experiments
Autor Gulkowska, A.; Thalmann, B.; Hollender, J.; Krauss, M. ORCID logo
Quelle Chemosphere
Erscheinungsjahr 2014
Department WANA
Band/Volume 107
Seite von 366
Seite bis 372
Sprache englisch
Keywords Sulfonamide antimicrobials; Nonextractable residues; Nucleophilic addition; Sequential extraction
UFZ Querschnittsthemen RU2;
Abstract Soil incubation experiments using 14C-labelled sulfamethazine were carried out to assess the factors governing its nonextractable residue (NER) formation via nucleophilic addition reactions. Circumstantial evidence on possible mechanisms of NER formation was derived from a selective manipulation of soil samples. The amount of quinones in soil available for nucleophilic addition was a limiting factor as indicated by (i) an (initial) increase of NER formation by adding quinone precursors or enhancing their formation by manganese oxide addition and (ii) a decrease of NER formation by limiting the formation of quinones under anaerobic conditions. A slow NER formation with time under aerobic conditions is likely caused by covalent bonding as well, because no slow NER formation phase was observed under anaerobic conditions.
dauerhafte UFZ-Verlinkung https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=14875
Gulkowska, A., Thalmann, B., Hollender, J., Krauss, M. (2014):
Nonextractable residue formation of sulfonamide antimicrobials: New insights from soil incubation experiments
Chemosphere 107 , 366 - 372 10.1016/j.chemosphere.2013.12.093