Details zur Publikation |
| Kategorie | Textpublikation |
| Referenztyp | Zeitschriften |
| DOI | 10.1016/j.chemosphere.2013.12.093 |
| Titel (primär) | Nonextractable residue formation of sulfonamide antimicrobials: New insights from soil incubation experiments |
| Autor | Gulkowska, A.; Thalmann, B.; Hollender, J.; Krauss, M.
|
| Quelle | Chemosphere |
| Erscheinungsjahr | 2014 |
| Department | WANA |
| Band/Volume | 107 |
| Seite von | 366 |
| Seite bis | 372 |
| Sprache | englisch |
| Keywords | Sulfonamide antimicrobials; Nonextractable residues; Nucleophilic addition; Sequential extraction |
| UFZ Querschnittsthemen | RU2; |
| Abstract | Soil incubation experiments using 14C-labelled sulfamethazine were carried out to assess the factors governing its nonextractable residue (NER) formation via nucleophilic addition reactions. Circumstantial evidence on possible mechanisms of NER formation was derived from a selective manipulation of soil samples. The amount of quinones in soil available for nucleophilic addition was a limiting factor as indicated by (i) an (initial) increase of NER formation by adding quinone precursors or enhancing their formation by manganese oxide addition and (ii) a decrease of NER formation by limiting the formation of quinones under anaerobic conditions. A slow NER formation with time under aerobic conditions is likely caused by covalent bonding as well, because no slow NER formation phase was observed under anaerobic conditions. |
| Gulkowska, A., Thalmann, B., Hollender, J., Krauss, M. (2014): Nonextractable residue formation of sulfonamide antimicrobials: New insights from soil incubation experiments Chemosphere 107 , 366 - 372 10.1016/j.chemosphere.2013.12.093 |
|