Details zur Publikation |
Kategorie | Textpublikation |
Referenztyp | Zeitschriften |
DOI | 10.1111/pai.12056 |
Volltext | Shareable Link |
Titel (primär) | Association of atopic and non-atopic asthma with emotional symptoms in school children |
Autor | Kohlboeck, G.; Koletzko, S.; Bauer, C.-P.; von Berg, A.; Berdel, D.; Krämer, U.; Schaaf, B.; Lehmann, I.; Herbarth, O.; Heinrich, J. |
Quelle | Pediatric Allergy and Immunology |
Erscheinungsjahr | 2013 |
Department | IMMU |
Band/Volume | 24 |
Heft | 3 |
Seite von | 230 |
Seite bis | 236 |
Sprache | englisch |
Keywords | asthma;atopy;allergy;behavior problems;epidemiology;depression;comorbidity;affective disorders |
UFZ Querschnittsthemen | RU3; |
Abstract | Objective: To date, there is conflicting evidence whether the association between asthma and depression depends on the atopic or non-atopic asthma phenotype. This study investigates associations between emotional symptoms and atopic and nonatopic asthma in school-aged children. Methods: Cross-sectional data on asthma and allergic diseases at the 10-year followup of two birth cohorts were collected by parent-reported physician diagnoses. Specific IgE levels including most common inhalant allergens (SX1) and food allergens (FX5) were measured by RAST-CAP FEIA. Atopic asthma was defined as asthma ever and positive specific IgE test, non-atopic asthma as asthma ever and no IgE sensitization. Emotional symptoms were assessed by parent-reported strength and difficulty questionnaire. Logistic regression modeling were applied to determine likelihood of emotional symptoms in children with atopic and non-atopic asthma controlling for socio-demographic factors, body mass index, atopic eczema, allergic rhinitis, and pubertal development. Results: Non-atopic asthma was associated with about 3-fold higher likelihood of emotional symptoms compared to children with no asthma (ORadj = 2.90, CI95% = 1.46–5.73). Atopic asthma was not associated with emotional symptoms (ORadj = 1.35, CI95% = 0.81–2.26). Conclusions: Atopic and non-atopic asthma in children might have different etiologies, whereas for non-atopic asthma, emotional symptoms are relevant, this is not the case in atopic asthma. The relationship between the non-atopic asthma phenotype and emotional symptoms might be dependent on gender. |
dauerhafte UFZ-Verlinkung | https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=13686 |
Kohlboeck, G., Koletzko, S., Bauer, C.-P., von Berg, A., Berdel, D., Krämer, U., Schaaf, B., Lehmann, I., Herbarth, O., Heinrich, J. (2013): Association of atopic and non-atopic asthma with emotional symptoms in school children Pediatr. Allergy Immunol. 24 (3), 230 - 236 10.1111/pai.12056 |