Details zur Publikation

Referenztyp Zeitschriften
DOI / URL Link
Titel (primär) Overview of organohalide-respiring bacteria and a proposal for a classification system for reductive dehalogenases
Autor Hug, L.A.; Maphosa, F.; Leys, D.; Löffler, F.E.; Smidt, H.; Edwards, E.A.; Adrian, L.;
Journal / Serie Philosophical Transactions of the Royal Society B-Biological Sciences
Erscheinungsjahr 2013
Department ISOBIO;
Band/Volume 368
Heft 1616
Sprache englisch;
POF III (gesamt) T41;
Supplements https://royalsocietypublishing.org/action/downloadSupplement?doi=10.1098%2Frstb.2012.0322&file=rstb20120322supp1.pdf
Keywords organohalide respiration; reductive dehalogenase; phylogenetics
UFZ Querschnittsthemen ru3
Abstract

Organohalide respiration is an anaerobic bacterial respiratory process that uses halogenated hydrocarbons as terminal electron acceptors during electron transport-based energy conservation. This dechlorination process has triggered considerable interest for detoxification of anthropogenic groundwater contaminants. Organohalide-respiring bacteria have been identified from multiple bacterial phyla, and can be categorized as obligate and non-obligate organohalide respirers. The majority of the currently known organohalide-respiring bacteria carry multiple reductive dehalogenase genes. Analysis of a curated set of reductive dehalogenases reveals that sequence similarity and substrate specificity are generally not correlated, making functional prediction from sequence information difficult. In this article, an orthologue-based classification system for the reductive dehalogenases is proposed to aid integration of new sequencing data and to unify terminology.

ID 13590
dauerhafte UFZ-Verlinkung https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=13590
Hug, L.A., Maphosa, F., Leys, D., Löffler, F.E., Smidt, H., Edwards, E.A., Adrian, L. (2013):
Overview of organohalide-respiring bacteria and a proposal for a classification system for reductive dehalogenases
Philos. Trans. R. Soc. B-Biol. Sci. 368 (1616), art. 20120322