Details zur Publikation

Kategorie Textpublikation
Referenztyp Zeitschriften
DOI 10.1007/s00216-012-5717-0
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Titel (primär) Membrane-assisted solvent extraction coupled to large volume injection-gas chromatography-mass spectrometry for the determination of a variety of endocrine disrupting compounds in environmental water samples
Autor Iparraguirre Izaga, A.; Navarro, P.; Prieto, A.; Rodil, R.; Olivares, M.; Fernández, L.-A.; Zuloaga, O.
Quelle Analytical and Bioanalytical Chemistry
Erscheinungsjahr 2012
Department OEC; ANA
Band/Volume 402
Heft 9
Seite von 2897
Seite bis 2907
Sprache englisch
Keywords Endocrine disrupting compounds; Environmental water samples; Membrane-assisted solvent extraction; Gas chromatography–mass spectrometry; Large volume injection
Abstract

Membrane-assisted solvent extraction coupled to large volume injection in a programmable temperature vaporisation injector using gas chromatography–mass spectrometry analysis was optimised for the simultaneous determination of a variety of endocrine disrupting compounds in environmental water samples (estuarine, river and wastewater). Among the analytes studied, certain hormones, alkylphenols and bisphenol A were included. The nature of membranes, extraction solvent, extraction temperature, solvent volume, extraction time, ionic strength and methanol addition were evaluated during the optimisation of the extraction. Matrix effects during the extraction step were studied in different environmental water samples: estuarine water, river water and wastewater (influent and effluent). Strong matrix effects were observed for most of the compounds in influent and effluent samples. Different approaches were studied in order to correct or minimise matrix effects, which included the use of deuterated analogues, matrix-matched calibration, standard addition calibration, dilution of the sample and clean-up of the extract using solid-phase extraction (SPE). The use of deuterated analogues corrected satisfactorily matrix effect for estuarine and effluent samples for most of the compounds. However, in the case of influent samples, standard addition calibration and dilution of the sample were the best approaches. The SPE clean-up provided similar recoveries to those obtained after correction with the corresponding deuterated analogue but better chromatographic signal was obtained in the case of effluent samples. Method detection limits in the 5–54 ng L−1 range and precision, calculated as relative standard deviation, in the 2–25% range were obtained.
dauerhafte UFZ-Verlinkung https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=12289
Iparraguirre Izaga, A., Navarro, P., Prieto, A., Rodil, R., Olivares, M., Fernández, L.-A., Zuloaga, O. (2012):
Membrane-assisted solvent extraction coupled to large volume injection-gas chromatography-mass spectrometry for the determination of a variety of endocrine disrupting compounds in environmental water samples
Anal. Bioanal. Chem. 402 (9), 2897 - 2907 10.1007/s00216-012-5717-0