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Referenztyp Zeitschriften
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Titel (primär) Polyparameter linear free energy models for polyacrylate fiber-water partition coefficients to evaluate the efficiency of solid-phase microextraction
Autor Endo, S.; Droge, S.T.J.; Goss, K.-U.;
Journal / Serie Analytical Chemistry
Erscheinungsjahr 2011
Department AUC;
Band/Volume 83
Heft 4
Sprache englisch;
Abstract The fiber-water partition coefficient, Kfw, is decisive for performance of solid-phase microextraction (SPME) techniques in organic chemical analyses. In this study, polyacrylate (PA)-coated fiber was evaluated for its Kfw values toward diverse neutral organic compounds. Literature Kfw data were thoroughly evaluated, and additional Kfw values for 69 compounds were measured in phosphate-buffered saline (PBS) solution at 37 °C. These Kfw data, spanning over 6 orders of magnitude, were used to construct polyparameter linear free energy relationship (PP-LFER) models. The PP-LFER models fit well to the data with a standard deviation of 0.15-0.23 log units. Additional experiments indicated that the differences in temperature (25 vs 37 °C), electrolyte concentrations (pure water vs PBS), and conditioning methods (heat vs methanol) had only minor influences (<0.3 log units) on Kfw. Using the established PP-LFERs, the SPME extraction efficiency of PA coating toward compounds of differing polarity was evaluated in comparison to poly(dimethylsiloxane) (PDMS) coating. PA exhibited higher extraction capacities for H-bond donor compounds (e.g., phenols, anilines, amides, and many drugs and pesticides) with the estimated Kfw values being 1-4 log units higher than those of PDMS. Also, PA was shown to be more efficient than PDMS for hydrophobic aromatic compounds.
ID 10743
dauerhafte UFZ-Verlinkung https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=10743
Endo, S., Droge, S.T.J., Goss, K.-U. (2011):
Polyparameter linear free energy models for polyacrylate fiber-water partition coefficients to evaluate the efficiency of solid-phase microextraction
Anal. Chem. 83 (4), 1394 - 1400