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ID Publikation
21185 Adam, I., Dewi, D.L., Mooiweer, J., Sadik, A., Mohapatra, S.R., Berdel, B., Keil, M., Sonner, J.K., Thedieck, K., Rose, A.J., Platten, M., Heiland, I., Trump, S., Opitz, C.A. (2018):
Upregulation of tryptophanyl-tRNA synthethase adapts human cancer cells to nutritional stress caused by tryptophan degradation
Oncoimmunology 7 (12), e1486353
Volltext (DOI)
18223 Dewi, D.L., Mohapatra, S.R., Cabañes, S.B., Adam, I., Patterson, L.F.S., Berdel, B., Kahloon, M., Thürmann, L., Loth, S., Heilmann, K., Weichenhan, D., Mücke, O., Heiland, I., Wimberger, P., Kuhlmann, J.D., Kellner, K.-H., Schott, S., Plass, C., Platten, M., Gerhäuser, C., Trump, S., Opitz, C.A. (2017):
Suppression of indoleamine-2,3-dioxygenase 1 expression by promoter hypermethylation in ER-positive breast cancer
Oncoimmunology 6 (2), e1274477
Volltext (DOI)
18890 Dewi, D.L., Mohapatra, S., Wimberger, P., Kuhlmann, J.D., Schott, S., Kellner, K.-H., Gerhauser, C., Trump, S., Opitz, C.A. (2017):
Epigenetic regulation of indoleamine-2,3-dioxygenase 1 expression in human breast cancer
Breast 32 (Suppl. 1), S31 - S32
Volltext (DOI)
14754 Litzenburger, U.M., Opitz, C.A., Sahm, F., Rauschenbach, K.J., Trump, S., Winter, M., Ott, M., Ochs, K., Lutz, C., Liu, X., Anastasov, N., Lehmann, I., Höfer, T., von Deimling, A., Wick, W., Platten, M. (2014):
Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR
Oncotarget 5 (4), 1038 - 1051
Volltext (DOI)
11625 Opitz, C.A., Litzenburger, U.M., Sahm, F., Ott, M., Tritschler, I., Trump, S., Schumacher, T., Jestaedt, L., Schrenk, D., Weller, M., Jugold, M., Guillemin, G.J., Miller, C.L., Lutz, C., Radlwimmer, B., Lehmann, I., von Deimling, A., Wick, W., Platten, M. (2011):
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
Nature 478 (7368), 197 - 203
Volltext (DOI)
23546 Sadik, A., Somarribas Patterson, L.F., Öztürk, S., Mohapatra, S.R., Panitz, V., Secker, P.F., Pfänder, P., Loth, S., Salem, H., Prentzell, M.T., Berdel, B., Iskar, M., Faessler, E., Reuter, F., Kirst, I., Kalter, V., Foerster, K.I., Jäger, E., Ramallo Guevara, C., Sobeh, M., Hielscher, T., Poschet, G., Reinhardt, A., Hassel, J.C., Zapatka, M., Hahn, U., von Deimling, A., Hopf, C., Schlichting, R., Escher, B.I., Burhenne, J., Haefeli, W.E., Ishaque, N., Böhme, A., Schäuble, S., Thedieck, K., Trump, S., Seiffert, M., Opitz, C.A. (2020):
IL4I1 is a metabolic immune checkpoint that activates the AHR and promotes tumor progression
Cell 182 (5), 1252 - 1270.e34
Volltext (DOI)
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