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Contact us

kai-uwe.goss@ufz.de

News

We are happy to welcome our new PhD student Estella Garessus. Estella will focus on the toxicokinetic-modelling in rat.

We updated our LSER Database in Dezember 2017. We upgraded the Extraction Tool and offer now two more tools, one to calculate the membrane permeability (Caco-2 test) and one to calculate c_free in plasma and different cell assays.

LSER DB

Publications

Bittermann, K., Linden, L., Goss, K.-U., (2018):
Screening tools for the bioconcentration potential of monovalent organic ions in fish
Environ. Sci.-Proc. Imp. 20 (5), 845 - 853
full text (url)
Ebert, A., Hannesschlaeger, C., Goss, K.-U., Pohl, P., (2018):
Passive permeability of planar lipid bilayers to organic anions
Biophys. J. 115 (10), 1931 - 1941
full text (url)
Fischer, F.C., Abele, C., Droge, S.T.J., Henneberger, L., König, M., Schlichting, R., Scholz, S., Escher, B.I., (2018):
Cellular uptake kinetics of neutral and charged chemicals in in vitro assays measured by fluorescence microscopy
Chem. Res. Toxicol. 31 (8), 646 - 657
full text (url)
Goss, K.U., Bittermann, K., (2018):
Predicting apparent passive permeability of Caco-2 and MDCK cell-monolayers: A mechanistic model
Naunyn-Schmiedebergs Arch. Pharmacol. 391 (Suppl. 1), S14 - S14
full text (url)
Goss, K.-U., Bittermann, K., Henneberger, L., Linden, L., (2018):
Equilibrium biopartitioning of organic anions - A case study for humans and fish
Chemosphere 199 , 174 - 181
full text (url)
Goss, K.-U., Linden, L., Ulrich, N., Schlechtriem, C., (2018):
Revisiting elimination half live as an indicator for bioaccumulation in fish and terrestrial mammals
Chemosphere 210 , 341 - 346
full text (url)
Kopinke, F.-D., Georgi, A., Goss, K.-U., (2018):
Comment on "Mistakes and inconsistencies regarding adsorption of contaminants from aqueous solutions: A critical review, published by Tran et al. [Water Research 12, 2017, 88-116]"
Water Res. 129 , 520 - 521
final draft (pdf)
Kopinke, F.-D., Georgi, A., Goss, K.-U., (2018):
Comment on "Re-evaluation of the century-old Langmuir isotherm for modeling adsorption phenomena in solution", published by Azizian et al. [Chemical physics 513 (2018) 99–104]
Chem. Phys.
full text (url)
Krause, S., Goss, K.-U., (2018):
The impact of desorption kinetics from albumin on hepatic extraction efficiency and hepatic clearance: a model study
Arch. Toxicol. 92 (7), 2175 - 2182
full text (url)
Krause, S., Goss, K.-U., (2018):
In vitro–in vivo extrapolation of hepatic metabolism for different scenarios - a toolbox
Chem. Res. Toxicol. 31 (11), 1195 - 1202
full text (url)
Krause, S., Goss, K.U., (2018):
Desorption kinetics of organic chemicals from albumin
Naunyn-Schmiedebergs Arch. Pharmacol. 391 (Suppl. 1), S45 - S45
full text (url)
Krause, S., Ulrich, N., Goss, K.-U., (2018):
Desorption kinetics of organic chemicals from albumin
Arch. Toxicol. 92 (3), 1065 - 1074
full text (url)
Larisch, W., Goss, K.-U., (2018):
Uptake, distribution and elimination of chemicals in fish – Which physiological parameters are the most relevant for toxicokinetics?
Chemosphere 210 , 1108 - 1114
full text (url)
Larisch, W., Goss, K.-U., (2018):
Modelling oral up-take of hydrophobic and super-hydrophobic chemicals in fish
Environ. Sci.-Proc. Imp. 20 (1), 98 - 104
full text (url)
Ulrich, N., Bury, D., Koch, H.M., Rüther, M., Weber, T., Käfferlein, H.-U., Weiss, T., Brüning, T., Kolossa‑Gehring, M., (2018):
Metabolites of the alkyl pyrrolidone solvents NMP and NEP in 24-h urine samples of the German Environmental Specimen Bank from 1991 to 2014
Int. Arch. Occup. Environ. Health 91 (8), 1073 - 1082
full text (url)
Wang, C., Wania, F., Goss, K.-U., (2018):
Is secondary organic aerosol yield governed by kinetic factors rather than equilibrium partitioning?
Environ. Sci.-Proc. Imp. 20 (1), 245 - 252
full text (url)