Publication Details
Category Text Publication
Reference Category Journals
DOI 10.1002/rcm.3910
Title (Primary) Comparison of atmospheric pressure photoionization and electrospray ionization mass spectrometry for the analysis of UV filters
Author Rodil, R.; Schrader, S.; Moeder, M.
Source Titel Rapid Communications in Mass Spectrometry
Year 2009
Department ANA; UV
Volume 23
Issue 5
Page From 580
Page To 588
Language englisch
Abstract A comparison was made between the electrospray ionization (ESI) and atmospheric pressure photoionization (APPI) tandem mass spectrometric (MS/MS) responses of eleven ultraviolet (UV) filters. Four of the target compounds were favourably ionized in negative ion mode, and the other seven compounds in positive ion mode. For nine of the compounds APPI generated a similar response to that of ESI, but the APPI signal-to-noise (S/N) ratios were 1.3-60 times higher. The two most polar of the UV filter compounds (PBSA and BP-4) were more efficiently ionized by ESI, offering higher signal intensities and lower detection limits. APPI was, however, less susceptible to ion suppression than ESI when real samples were injected. In order to optimize the APPI conditions different dopant solvents were examined to enhance the efficiency of the photoionization process. Among the evaluated dopants, toluene was selected as the best compromise. At a toluene flow rate of 10% of the solvent flow rates the ionization response increased by a factor of 40-50 over the use of no dopant for the compounds in positive ion mode and by more than 300 for the compounds in negative ion mode. Copyright © 2009 John Wiley & Sons, Ltd.
Persistent UFZ Identifier https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=532
Rodil, R., Schrader, S., Moeder, M. (2009):
Comparison of atmospheric pressure photoionization and electrospray ionization mass spectrometry for the analysis of UV filters
Rapid Commun. Mass Spectrom. 23 (5), 580 - 588 10.1002/rcm.3910