Publication Details |
| Category | Text Publication |
| Reference Category | Book chapters |
| DOI | 10.1016/S1873-0140(05)80005-0 |
| Title (Primary) | Use of fish cell lines in the toxicology and ecotoxicology of fish. Piscine cell lines in environmental toxicology |
| Title (Secondary) | Environmental toxicology |
| Author | Bols, N.C.; Dayeh, V.R.; Lee, L.E.J.; Schirmer, K. |
| Publisher | Mommsen, T.P.; Moon, T.W. |
| Source Titel | Biochemistry and Molecular Biology of Fishes |
| Year | 2005 |
| Department | ZELLTOX |
| Volume | 6 |
| Page From | 43 |
| Page To | 84 |
| Language | englisch |
| Abstract | This chapter reviews the uses of one type, cell lines, in fish environmental toxicology and describes the nature of animal cell cultures. From the perspective of ecotoxicants, fish are especially important. Ecotoxicants are often released first into aquatic environments by a variety of routes. As many biological systems have been preserved throughout evolution, effects on the fish can serve as a warning of possible impacts on human health and fish can serve as laboratory models for studying ecotoxicants of concern to human health. Understanding the impact of ecotoxicants on the fish is of economic importance. Toxicology studies the effects of toxicants on individual organisms and ecotoxicology studies the impact of ecotoxicants on ecosystems. Both toxicology and ecotoxicology try to integrate toxicological information through the various hierarchical levels of biological organization, striving ultimately to explain the impact of toxicants on individuals and ecosystems. The chapter explains the advantages of animal cell cultures and toxicology applications and ecotoxicology applications of fish cell lines. The chapter evaluates common cellular responses with the help of cytotoxicit, cell growth, genotoxicity, and xenobiotic metabolism. |
| Persistent UFZ Identifier | https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=3208 |
| Bols, N.C., Dayeh, V.R., Lee, L.E.J., Schirmer, K. (2005): Use of fish cell lines in the toxicology and ecotoxicology of fish. Piscine cell lines in environmental toxicology In: Mommsen, T.P., Moon, T.W. (eds.) Environmental toxicology Biochemistry and Molecular Biology of Fishes 6 Elsevier, Amsterdam, p. 43 - 84 10.1016/S1873-0140(05)80005-0 |
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