Department of Bioanalytical Ecotoxicology. Photo: Prof. Dr. Rolf Altenburger/UFZ

Department of Bioanalytical Ecotoxicology

Modern societies deal with chemicals in large numbers and quantities. The fate and effect of chemicals in the environment depends on the properties of the organisms exposed to them, the environmental system and on the compound. But what determines the biologically relevant dose of chemicals? How does a cumulative dose become biological action? And how do combined effects translate into adverse outcome?

Our research strives to assess potential adverse mixture effects based on a mechanistic understanding of biological action. Our goal is to provide bioanalytical tools for environmental risk detection and chemical safety assessment. An essential part of our work in the Department of Bioanalytical Ecotoxicology is to establish dose-response relationships.

Our current research focuses on physiology-based toxicokinetics, adverse outcome pathways and multiple stress diagnosis in fish and plant model systems.

We communicate our research to the public in the form of original publications, innovative methods, extrapolation tools, expert statements and consultancy on potentially adverse effects of chemical mixtures in the environment. Furthermore, we provide ample training opportunities for young researchers.