Fish and frog embryos

Fish and amphibian embryos as alternative models in toxicology and teratology

No symposium planned for 2020

The 6th international symposium and workshop is scheduled for 2022



Fish and amphibian embryo models are highly popular in the area of toxicology, both in research, industry and potential regulatory application. These models exhibit a number of advantages which make them superior and/or complementary to others. In compliance with international animal welfare regulations, the fish and amphibian embryo models provide an ethically acceptable small scale analysis system with the complexity of a complete organism. A suite of available advanced methodologies allows various types of experimental approaches ranging from phenotypic observations, functional assays to “omics” analysis. The ultimate goal of the symposium is to promote the development of the fish and frog embryo models as potential alternatives to animal testing.
Five exciting symposia were held between 2010 and 2018 with a strong focus on the zebrafish model. The symposium aims to bring together scientists using fish and frog embryo models, exchange knowledge, ideas and latest developments in the field of toxicology and teratology. Invited lectures will focus on specific topics. Breakout sessions will allow to discuss major advantages, limitations, new fields and future research needs of the fish/amphibian embryo model and to establish collaborations. Technical workshop aim to provide the community with training on advanced approaches for fish embryo toxicity assessments.

Due to an special SETAC conference with overlapping scope (originally planned for 2020) and the COVID-19 pandemy we have not considered organisation of a symposium for 2020. The 6th symposium will likely be organised in 2022 within our biannual schedule.

Contributions welcome

Contributions from participants, both poster presentations and platform presentations are welcome. These presentations could cover one of the following topics: human toxicology screening, teratogenicity, nanotoxicology, immunotoxicity, regulatory toxicology, endocrine effects, neurotoxicity, toxicogenomics (‘omics‘), high throughput technologies, functional genomics, ethics/animal welfare and ecotoxicology (acute and chronic toxicity, bioconcentration, effluent testing). Presentations can be made in the general platform or in breakout sessions with specific topics.

For further questions please contact Stefan Scholz, Helmholtz Centre for Environmental Research, Leipzig, Germany (+49 341 235 1080)

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Stefan Scholz

Marc Léonard

Scientific organising committee

Stefan Scholz UFZ
Mark Léonard L'Oréal
Noémie de Crozé L'Oréal
Jessica Legradi IVM (VU Amsterdam)
Aldert Piersma RIVM
Peter de Witte Univ. Leuven
Stephanie Padilla US EPA
Juliette Legler IRAS (Utrecht Univ.)

An activity of the UFZ research programme: